1-(benzotriazol-1-yl)-1-phenoxy-p-methylacetophenone p-tosylhydrazone

Base Information

• Chemical Name: 1-(benzotriazol-1-yl)-1-phenoxy-p-methylacetophenone p-tosylhydrazone
• CAS No.: 189343-64-4
• Molecular Formula: C₂₈H₂₅N₅O₃S
• Molecular Weight: 511.604
• Mol file: 189343-64-4.mol

Synonyms:1-(benzotriazol-1-yl)-1-phenoxy-p-methylacetophenone p-tosylhydrazone

Chemical Property of 1-(benzotriazol-1-yl)-1-phenoxy-p-methylacetophenone p-tosylhydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(benzotriazol-1-yl)-1-phenoxy-p-methylacetophenone p-tosylhydrazone

There total 3 articles about 1-(benzotriazol-1-yl)-1-phenoxy-p-methylacetophenone p-tosylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

toluene-4-sulfonic acid hydrazide (1576-35-8) + 2-Benzotriazol-1-yl-2-phenoxy-1-p-tolyl-ethanone (189343-51-9) → 1-(benzotriazol-1-yl)-1-phenoxy-p-methylacetophenone p-tosylhydrazone (189343-64-4)

Guidance literature:

In benzene; for 12h; Heating;

DOI:10.1021/jo962291t

Reference yield:

4-methyl-benzoic acid methyl ester (99-75-2) → 1-(benzotriazol-1-yl)-1-phenoxy-p-methylacetophenone p-tosylhydrazone (189343-64-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / n-BuLi / tetrahydrofuran; hexane / 12 h / -78 - 20 °C

2: 71 percent / benzene / 12 h / Heating

With n-butyllithium; In tetrahydrofuran; hexane; benzene;

DOI:10.1021/jo962291t

Reference yield:

1-(phenoxymethyl)-1H-benzo[d][1,2,3]triazole (111198-02-8) → 1-(benzotriazol-1-yl)-1-phenoxy-p-methylacetophenone p-tosylhydrazone (189343-64-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / n-BuLi / tetrahydrofuran; hexane / 12 h / -78 - 20 °C

2: 71 percent / benzene / 12 h / Heating

With n-butyllithium; In tetrahydrofuran; hexane; benzene;

DOI:10.1021/jo962291t

upstream raw materials:

toluene-4-sulfonic acid hydrazide

2-Benzotriazol-1-yl-2-phenoxy-1-p-tolyl-ethanone

4-methyl-benzoic acid methyl ester

1-(phenoxymethyl)-1H-benzo[d][1,2,3]triazole

Downstream raw materials:

1-(p-tolyl)-1-hexyne