2-(4-methoxy-benzylamino)-3-phenyl-propionic acid ethyl ester

Base Information

• Chemical Name: 2-(4-methoxy-benzylamino)-3-phenyl-propionic acid ethyl ester
• CAS No.: 338411-45-3
• Molecular Formula: C₁₉H₂₃NO₃
• Molecular Weight: 313.397
• Mol file: 338411-45-3.mol

Synonyms:2-(4-methoxy-benzylamino)-3-phenyl-propionic acid ethyl ester

Chemical Property of 2-(4-methoxy-benzylamino)-3-phenyl-propionic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-(4-methoxy-benzylamino)-3-phenyl-propionic acid ethyl ester

There total 1 articles about 2-(4-methoxy-benzylamino)-3-phenyl-propionic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(L)-phenylalanine ethyl ester hydrochloride (3182-93-2) + 4-methoxy-benzaldehyde (123-11-5) → 2-(4-methoxy-benzylamino)-3-phenyl-propionic acid ethyl ester (338411-45-3)

Guidance literature:

With sodium tris(acetoxy)borohydride; In dichloromethane; at 0 - 20 ℃;

DOI:10.1055/s-2007-967987

Reference yield: 100.0%

2-(4-methoxy-benzylamino)-3-phenyl-propionic acid ethyl ester (338411-45-3) + ethyl 3-(chlorocarbonyl)-3-butenoate (127566-69-2) → C26H31NO6

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; for 4h; Inert atmosphere;

DOI:10.3987/COM-19-S(F)56

Reference yield: 100.0%

2-(4-methoxy-benzylamino)-3-phenyl-propionic acid ethyl ester (338411-45-3) + Cinnamoyl chloride (102-92-1,17082-09-6) → C28H29NO4 (1431724-22-9)

Guidance literature:

In dichloromethane; at 20 ℃; for 4h;

DOI:10.1002/chem.201201339

upstream raw materials:

(L)-phenylalanine ethyl ester hydrochloride

4-methoxy-benzaldehyde

Downstream raw materials:

1,3-di((furan-2-yl)methyl)thiourea

C₂₂H₂₅NO₄

C₂₂H₂₅NO₄

C₂₈H₂₉NO₄