4-methoxy-2,6-dimethyl phenyl acetonitrile

Base Information

• Chemical Name: 4-methoxy-2,6-dimethyl phenyl acetonitrile
• CAS No.: 61000-23-5
• Molecular Formula: C₁₁H₁₃NO
• Molecular Weight: 175.23

Synonyms:4-methoxy-2,6-dimethyl phenyl acetonitrile

Chemical Property of 4-methoxy-2,6-dimethyl phenyl acetonitrile

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

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Technology Process of 4-methoxy-2,6-dimethyl phenyl acetonitrile

There total 4 articles about 4-methoxy-2,6-dimethyl phenyl acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4-methoxy-2,6-dimethylphenyl)methanol (61000-21-3) → 4-methoxy-2,6-dimethyl phenyl acetonitrile (61000-23-5)

Guidance literature:

With chloro-trimethyl-silane; NaCN; In dichloromethane; ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

sodium cyanide (773837-37-9) + C13H22NO(1+)*I(1-) → 4-methoxy-2,6-dimethyl phenyl acetonitrile (61000-23-5)

Guidance literature:

With 18-crown-6 ether; In N,N-dimethyl-formamide;

DOI:10.1021/jm9000242

Reference yield:

trimethylsilyl cyanide (7677-24-9) + 4-methoxy-2,6-dimethylbenzyl bromide (61000-22-4) → 4-methoxy-2,6-dimethyl phenyl acetonitrile (61000-23-5)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; acetonitrile; at 0 - 20 ℃; for 2h;

upstream raw materials:

(4-methoxy-2,6-dimethylphenyl)methanol

sodium cyanide

trimethylsilyl cyanide

4-methoxy-2,6-dimethylbenzyl bromide

Downstream raw materials:

C₁₃H₁₅NO₂

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