2,6-Dimethyl-4-methoxybenzyl bromide

Base Information

Chemical Name:2,6-Dimethyl-4-methoxybenzyl bromide
CAS No.:61000-22-4
Molecular Formula:C10H13BrO
Molecular Weight:229.117
Hs Code.:
DSSTox Substance ID:DTXSID90473567
Wikidata:Q72470851
Mol file:61000-22-4.mol

Synonyms:2,6-DIMETHYL-4-METHOXYBENZYL BROMIDE;61000-22-4;2-(BROMOMETHYL)-5-METHOXY-1,3-DIMETHYLBENZENE;Benzene, 2-(bromomethyl)-5-methoxy-1,3-dimethyl-;5-(Methoxy)-2-(bromomethyl)-1,3-dimethylbenzene;DTXSID90473567;AKOS015995346

Suppliers and Price of 2,6-Dimethyl-4-methoxybenzyl bromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2,6-DIMETHYL-4-METHOXYBENZYL BROMIDE 95.00%
5MG
$ 503.36

Alichem
2,6-Dimethyl-4-methoxybenzylbromide
1g
$ 1519.80

Alichem
2,6-Dimethyl-4-methoxybenzylbromide
500mg
$ 855.75

Alichem
2,6-Dimethyl-4-methoxybenzylbromide
250mg
$ 494.40

Total 12 raw suppliers

Chemical Property of 2,6-Dimethyl-4-methoxybenzyl bromide

Chemical Property:

Boiling Point:291℃
Flash Point:115℃
PSA：9.23000
Density:1.305
LogP:3.20690
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:228.01498
Heavy Atom Count:12
Complexity:126

Purity/Quality:

99% ^*data from raw suppliers

2,6-DIMETHYL-4-METHOXYBENZYL BROMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC(=C1CBr)C)OC

Technology Process of 2,6-Dimethyl-4-methoxybenzyl bromide

There total 4 articles about 2,6-Dimethyl-4-methoxybenzyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 61000-21-3
(4-methoxy-2,6-dimethylphenyl)methanol

: 61000-22-4
4-methoxy-2,6-dimethylbenzyl bromide

Guidance literature:: With carbon tetrabromide; triphenylphosphine; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In dichloromethane; at 0 - 20 ℃; for 0.5h;
DOI:10.1055/s-2002-34902

Reference yield:

: 874-63-5
3,5-dimethylmethoxybenzene

: 61000-22-4
4-methoxy-2,6-dimethylbenzyl bromide

Guidance literature:: Multi-step reaction with 4 steps

1: 82 percent / Br₂ / CH₂Cl₂ / 0.25 h / 0 °C

2: Li / tetrahydrofuran / 1 h

3: NaBH₄ / methanol / 0 °C

4: 73 percent / PPh₃; CBr₄ / Pd₂(dba)3 / CH₂Cl₂ / 0.5 h / 0 - 20 °C

With sodium tetrahydroborate; carbon tetrabromide; bromine; lithium; triphenylphosphine; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1055/s-2002-34902

Reference yield:

: 6267-34-1
2-bromo-5-methoxy-1,3-dimethyl-benzene

: 61000-22-4
4-methoxy-2,6-dimethylbenzyl bromide

Guidance literature:: Multi-step reaction with 3 steps

1: Li / tetrahydrofuran / 1 h

2: NaBH₄ / methanol / 0 °C

3: 73 percent / PPh₃; CBr₄ / Pd₂(dba)3 / CH₂Cl₂ / 0.5 h / 0 - 20 °C

With sodium tetrahydroborate; carbon tetrabromide; lithium; triphenylphosphine; tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1055/s-2002-34902