(2S,3R,4S,5R,6R,7S)-3,5-isopropylidenedioxy-7-(benzyloxy-diisopropyl-silanyloxy)-1-(4-methoxy-benzyloxy)-2,4,6-trimethylnonane

Base Information

Chemical Name:(2S,3R,4S,5R,6R,7S)-3,5-isopropylidenedioxy-7-(benzyloxy-diisopropyl-silanyloxy)-1-(4-methoxy-benzyloxy)-2,4,6-trimethylnonane
CAS No.:449174-19-0
Molecular Formula:C₃₆H₅₈O₆Si
Molecular Weight:614.938
Hs Code.:

Synonyms:(2S,3R,4S,5R,6R,7S)-3,5-isopropylidenedioxy-7-(benzyloxy-diisopropyl-silanyloxy)-1-(4-methoxy-benzyloxy)-2,4,6-trimethylnonane

Suppliers and Price of (2S,3R,4S,5R,6R,7S)-3,5-isopropylidenedioxy-7-(benzyloxy-diisopropyl-silanyloxy)-1-(4-methoxy-benzyloxy)-2,4,6-trimethylnonane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R,4S,5R,6R,7S)-3,5-isopropylidenedioxy-7-(benzyloxy-diisopropyl-silanyloxy)-1-(4-methoxy-benzyloxy)-2,4,6-trimethylnonane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R,4S,5R,6R,7S)-3,5-isopropylidenedioxy-7-(benzyloxy-diisopropyl-silanyloxy)-1-(4-methoxy-benzyloxy)-2,4,6-trimethylnonane

There total 11 articles about (2S,3R,4S,5R,6R,7S)-3,5-isopropylidenedioxy-7-(benzyloxy-diisopropyl-silanyloxy)-1-(4-methoxy-benzyloxy)-2,4,6-trimethylnonane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 449174-14-5
(2S,3R,4S,5R,6R,7S)-7-(benzyloxy-diisopropyl-silanyloxy)-1-(4-methoxy-benzyloxy)-2,4,6-trimethyl-nonane-3,5-diol

: 116-11-0
2-Methoxypropene

: 449174-19-0
(2S,3R,4S,5R,6R,7S)-3,5-isopropylidenedioxy-7-(benzyloxy-diisopropyl-silanyloxy)-1-(4-methoxy-benzyloxy)-2,4,6-trimethylnonane

Guidance literature:: With camphor-10-sulfonic acid; In N,N-dimethyl-formamide; at 0 ℃; for 1.5h;
DOI:10.1021/ol026046+

Reference yield:

: 449174-22-5
(2R,3RS)-3-(benzyloxy-diisopropyl-silanyloxy)-2-methyl-pentan-1-ol

: 449174-19-0
(2S,3R,4S,5R,6R,7S)-3,5-isopropylidenedioxy-7-(benzyloxy-diisopropyl-silanyloxy)-1-(4-methoxy-benzyloxy)-2,4,6-trimethylnonane

Guidance literature:: Multi-step reaction with 4 steps

1.1: 88 percent / Dess-Martin periodinane / CH₂Cl₂ / 0.5 h / 20 °C

2.1: Ti(i-PrO)4; TiCl₄; i-Pr₂NEt / CH₂Cl₂ / 1 h / -78 °C

2.2: 39 percent / CH₂Cl₂ / 0.33 h / -78 °C

3.1: 91 percent / Zn(BH₄)2 / CH₂Cl₂; diethyl ether / 2 h / -30 °C

4.1: 80 percent / CSA / dimethylformamide / 1.5 h / 0 °C

With titanium(IV) isopropylate; zinc(II) tetrahydroborate; camphor-10-sulfonic acid; titanium tetrachloride; Dess-Martin periodane; N-ethyl-N,N-diisopropylamine; In diethyl ether; dichloromethane; N,N-dimethyl-formamide; 1.1: Dess-Martin oxidation reaction;
DOI:10.1021/ol026046+

Reference yield:

: 449174-21-4
(1RS,2R)-benzyloxy-[1-ethyl-3-(4-methoxy-benzyloxy)-2-methyl-propoxy]-diisopropylsilane

: 449174-19-0
(2S,3R,4S,5R,6R,7S)-3,5-isopropylidenedioxy-7-(benzyloxy-diisopropyl-silanyloxy)-1-(4-methoxy-benzyloxy)-2,4,6-trimethylnonane

Guidance literature:: Multi-step reaction with 5 steps

1.1: 78 percent / DDQ / CH₂Cl₂; H₂O / 1.5 h / 20 °C / pH 7

2.1: 88 percent / Dess-Martin periodinane / CH₂Cl₂ / 0.5 h / 20 °C

3.1: Ti(i-PrO)4; TiCl₄; i-Pr₂NEt / CH₂Cl₂ / 1 h / -78 °C

3.2: 39 percent / CH₂Cl₂ / 0.33 h / -78 °C

4.1: 91 percent / Zn(BH₄)2 / CH₂Cl₂; diethyl ether / 2 h / -30 °C

5.1: 80 percent / CSA / dimethylformamide / 1.5 h / 0 °C

With titanium(IV) isopropylate; zinc(II) tetrahydroborate; camphor-10-sulfonic acid; titanium tetrachloride; Dess-Martin periodane; N-ethyl-N,N-diisopropylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In diethyl ether; dichloromethane; water; N,N-dimethyl-formamide; 2.1: Dess-Martin oxidation reaction;
DOI:10.1021/ol026046+