3-(2,2-Dibromo-vinyl)-2,2-dimethyl-cyclopropanecarboxylic acid (2-carboxy-ethylcarbamoyl)-(3-phenoxy-phenyl)-methyl ester

Base Information

• Chemical Name: 3-(2,2-Dibromo-vinyl)-2,2-dimethyl-cyclopropanecarboxylic acid (2-carboxy-ethylcarbamoyl)-(3-phenoxy-phenyl)-methyl ester
• CAS No.: 200798-77-2
• Molecular Formula: C₂₅H₂₅Br₂NO₆
• Molecular Weight: 595.285
• Mol file: 200798-77-2.mol

Synonyms:3-(2,2-Dibromo-vinyl)-2,2-dimethyl-cyclopropanecarboxylic acid (2-carboxy-ethylcarbamoyl)-(3-phenoxy-phenyl)-methyl ester

Chemical Property of 3-(2,2-Dibromo-vinyl)-2,2-dimethyl-cyclopropanecarboxylic acid (2-carboxy-ethylcarbamoyl)-(3-phenoxy-phenyl)-methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(2,2-Dibromo-vinyl)-2,2-dimethyl-cyclopropanecarboxylic acid (2-carboxy-ethylcarbamoyl)-(3-phenoxy-phenyl)-methyl ester

There total 9 articles about 3-(2,2-Dibromo-vinyl)-2,2-dimethyl-cyclopropanecarboxylic acid (2-carboxy-ethylcarbamoyl)-(3-phenoxy-phenyl)-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(2',2'-dibromoethenyl)-2,2-dimethylcyclopropanecarboxylic acid (53179-78-5,61914-48-5,63538-10-3,63597-73-9,63949-77-9,72691-16-8,72691-18-0,74560-76-2,59952-39-5) → 3-(2,2-Dibromo-vinyl)-2,2-dimethyl-cyclopropanecarboxylic acid (2-carboxy-ethylcarbamoyl)-(3-phenoxy-phenyl)-methyl ester (200798-77-2)

Guidance literature:

Multi-step reaction with 4 steps

1: SOCl₂ / 1 h / Heating

2: 49 percent / 144 h

3: 1.) dicyclohexylcarbodiimide, dimethylaminopyridine / 1.) CH₂Cl₂, 30 min, 2.) CH₂Cl₂, overnight

4: trifluoroacetic acid / 0.17 h

With dmap; thionyl chloride; dicyclohexyl-carbodiimide; trifluoroacetic acid;

DOI:10.1021/jf970438r

Reference yield:

deltametrin (52918-63-5) → 3-(2,2-Dibromo-vinyl)-2,2-dimethyl-cyclopropanecarboxylic acid (2-carboxy-ethylcarbamoyl)-(3-phenoxy-phenyl)-methyl ester (200798-77-2)

Guidance literature:

Multi-step reaction with 5 steps

1: 55 percent / 1 M aq. NaOH / tetrahydrofuran / 72 h / Heating

2: SOCl₂ / 1 h / Heating

3: 49 percent / 144 h

4: 1.) dicyclohexylcarbodiimide, dimethylaminopyridine / 1.) CH₂Cl₂, 30 min, 2.) CH₂Cl₂, overnight

5: trifluoroacetic acid / 0.17 h

With dmap; sodium hydroxide; thionyl chloride; dicyclohexyl-carbodiimide; trifluoroacetic acid; In tetrahydrofuran;

DOI:10.1021/jf970438r

Reference yield:

(RS)-α-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylate (52315-07-8,65731-83-1,65731-84-2,65732-07-2,66290-20-8,66290-21-9,66841-24-5,67375-30-8,70982-01-3,70982-02-4,71697-59-1,72204-43-4,72204-44-5,83860-31-5,83860-32-6,137430-99-0,137432-55-4) → 3-(2,2-Dibromo-vinyl)-2,2-dimethyl-cyclopropanecarboxylic acid (2-carboxy-ethylcarbamoyl)-(3-phenoxy-phenyl)-methyl ester (200798-77-2)

Guidance literature:

Multi-step reaction with 5 steps

1: 1 M aq. NaOH / tetrahydrofuran / 36 h / Heating

2: concd. HCl

3: 49 percent / 144 h

4: 1.) dicyclohexylcarbodiimide, dimethylaminopyridine / 1.) CH₂Cl₂, 30 min, 2.) CH₂Cl₂, overnight

5: trifluoroacetic acid / 0.17 h

With hydrogenchloride; dmap; sodium hydroxide; dicyclohexyl-carbodiimide; trifluoroacetic acid; In tetrahydrofuran;

DOI:10.1021/jf970438r

upstream raw materials:

3-(2,2-Dibromo-vinyl)-2,2-dimethyl-cyclopropanecarboxylic acid (2-tert-butoxycarbonyl-ethylcarbamoyl)-(3-phenoxy-phenyl)-methyl ester

3-(2',2'-dibromoethenyl)-2,2-dimethylcyclopropanecarboxylic acid

2-hydroxy-2-(3-phenoxyphenyl)acetonitrile

3-phenoxymandelic acid