2-(dimethylamino)-2-phenylacetic acid (hydrochloride salt)

Base Information

Chemical Name:2-(dimethylamino)-2-phenylacetic acid (hydrochloride salt)
CAS No.:58685-78-2
Molecular Formula:C₁₀H₁₃NO₂*ClH
Molecular Weight:215.68
Hs Code.:

Synonyms:2-(dimethylamino)-2-phenylacetic acid (hydrochloride salt)

Suppliers and Price of 2-(dimethylamino)-2-phenylacetic acid (hydrochloride salt)

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 4 raw suppliers

Chemical Property of 2-(dimethylamino)-2-phenylacetic acid (hydrochloride salt)

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of 2-(dimethylamino)-2-phenylacetic acid (hydrochloride salt)

There total 3 articles about 2-(dimethylamino)-2-phenylacetic acid (hydrochloride salt) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 6319-70-6
ethyl α-N,N-dimethylphenyl acetate

: 58685-78-2,1353887-53-2
2-(dimethylamino)-2-phenylacetic acid (hydrochloride salt)

Guidance literature:: With hydrogenchloride; In water; at 120 ℃; for 2h; Sealed; Microwave irradiation;

Reference yield: 78.3%

: 4870-65-9,31302-84-8
2-bromophenylacetic acid

: 124-40-3
dimethyl amine

: 58685-78-2,1353887-53-2
2-(dimethylamino)-2-phenylacetic acid (hydrochloride salt)

Guidance literature:: 2-bromophenylacetic acid; dimethyl amine; In acetone; at 5 - 20 ℃; for 1h;

With hydrogenchloride; pH=3 - 4;

Reference yield:

: 611-74-5
N,N-dimethylbenzamide

: 58685-78-2,1353887-53-2
2-(dimethylamino)-2-phenylacetic acid (hydrochloride salt)

Guidance literature:: Multi-step reaction with 2 steps

1.1: bis(triphenylphosphine)iridium(I) carbonyl chloride / toluene / 0.08 h / 20 °C

1.2: 0.08 h / 20 °C

1.3: 0.5 h / 20 °C

2.1: hydrogenchloride / dichloromethane; water / 24 h / Reflux

With hydrogenchloride; bis(triphenylphosphine)iridium(I) carbonyl chloride; In dichloromethane; water; toluene;
DOI:10.1002/anie.201612367