4-Pyrimidinecarboxylicacid,5-ethyl-1,6-dihydro-2-methyl-6-oxo-,ethylester(9CI)

Base Information

Chemical Name:4-Pyrimidinecarboxylicacid,5-ethyl-1,6-dihydro-2-methyl-6-oxo-,ethylester(9CI)
CAS No.:744253-35-8
Molecular Formula:C₁₀H₁₄N₂O₃
Molecular Weight:210.233
Hs Code.:
Mol file:744253-35-8.mol

Synonyms:4-Pyrimidinecarboxylicacid,5-ethyl-1,6-dihydro-2-methyl-6-oxo-,ethylester(9CI)

Suppliers and Price of 4-Pyrimidinecarboxylicacid,5-ethyl-1,6-dihydro-2-methyl-6-oxo-,ethylester(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 4-Pyrimidinecarboxylicacid,5-ethyl-1,6-dihydro-2-methyl-6-oxo-,ethylester(9CI)

Chemical Property:

PSA：72.31000
LogP:1.22970

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-Pyrimidinecarboxylicacid,5-ethyl-1,6-dihydro-2-methyl-6-oxo-,ethylester(9CI)

There total 1 articles about 4-Pyrimidinecarboxylicacid,5-ethyl-1,6-dihydro-2-methyl-6-oxo-,ethylester(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 26103-77-5
2-Ethyl-3-oxo-succinic acid diethyl ester

: 124-42-5
acetamidine hydrochloride

: 744253-35-8
5-ethyl-6-hydroxy-2-methyl-pyrimidine-4-carboxylic acid ethyl ester

Guidance literature:: With sodium ethanolate; In ethanol;
DOI:10.1016/j.bmcl.2004.05.072

Reference yield:

: 744253-35-8
5-ethyl-6-hydroxy-2-methyl-pyrimidine-4-carboxylic acid ethyl ester

: [6-(cyclopropylmethyl-propyl-amino)-5-ethyl-2-methyl-pyrimidin-4-yl]-(2,4,6-trimethyl-phenyl)-methanone

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / POCl₃ / Heating

2: 90 percent / Heating

3: tetrahydrofuran

With trichlorophosphate; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2004.05.072