9-(2,6-dimethoxyphenyl)-1,8-dimethoxy-9Hthioxanthene

Base Information

• Chemical Name: 9-(2,6-dimethoxyphenyl)-1,8-dimethoxy-9Hthioxanthene
• CAS No.: 1259383-94-2
• Molecular Formula: C₂₃H₂₂O₄S
• Molecular Weight: 394.491
• Mol file: 1259383-94-2.mol

Synonyms:9-(2,6-dimethoxyphenyl)-1,8-dimethoxy-9Hthioxanthene

Chemical Property of 9-(2,6-dimethoxyphenyl)-1,8-dimethoxy-9Hthioxanthene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9-(2,6-dimethoxyphenyl)-1,8-dimethoxy-9Hthioxanthene

There total 21 articles about 9-(2,6-dimethoxyphenyl)-1,8-dimethoxy-9Hthioxanthene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

9-(2,6-dimethoxyphenyl)-1,8-dimethoxy-thioxanthenium tetrafluoroborate → 9-(2,6-dimethoxyphenyl)-1,8-dimethoxy-9Hthioxanthene (1259383-94-2)

Guidance literature:

With tetrabutylammonium borohydride; In dichloromethane; at 20 ℃; for 0.00833333h;

DOI:10.1002/poc.1753

Reference yield:

2-Methoxybenzoic acid (579-75-9) → 9-(2,6-dimethoxyphenyl)-1,8-dimethoxy-9Hthioxanthene (1259383-94-2)

Guidance literature:

Multi-step reaction with 7 steps

1.1: thionyl chloride / 0.5 h / 40 °C

2.1: dichloromethane / 1 h / 25 °C

3.1: N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium / tetrahydrofuran / 1 h / -78 °C

3.2: 12 h / 25 °C

4.1: lithium cyclohexylisopropylamide / tetrahydrofuran / 0.17 h / -20 °C

4.2: 20 h / 25 °C

5.1: n-butyllithium; N,N,N,N,-tetramethylethylenediamine / hexane; toluene / 2.25 h / 0 - 20 °C

5.2: 24 h / 50 °C

6.1: tetrafluoroboric acid / ethanol; water / 1 h

7.1: tetrabutylammonium borohydride / dichloromethane / 0.01 h / 20 °C

With tetrafluoroboric acid; n-butyllithium; thionyl chloride; N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; lithium cyclohexylisopropylamide; tetrabutylammonium borohydride; In tetrahydrofuran; ethanol; hexane; dichloromethane; water; toluene;

DOI:10.1002/poc.1753

Reference yield:

1,8-dimethoxy-9H-thioxanthen-9-one (123251-42-3) → 9-(2,6-dimethoxyphenyl)-1,8-dimethoxy-9Hthioxanthene (1259383-94-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: n-butyllithium; N,N,N,N,-tetramethylethylenediamine / hexane; toluene / 2.25 h / 0 - 20 °C

1.2: 24 h / 50 °C

2.1: tetrafluoroboric acid / ethanol; water / 1 h

3.1: tetrabutylammonium borohydride / dichloromethane / 0.01 h / 20 °C

With tetrafluoroboric acid; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; tetrabutylammonium borohydride; In ethanol; hexane; dichloromethane; water; toluene;

DOI:10.1002/poc.1753

upstream raw materials:

propylamine

9-(2,6-dimethoxyphenyl)-1,8-dimethoxy-9H-thioxanthen-9-ol

n-Octylamine

N,N-diethyl-2-methoxybenzamide