1-(2,3-Dihydrobenzofuran-5-yl)-2,2,2-trifluoroethanone

Base Information

Chemical Name:1-(2,3-Dihydrobenzofuran-5-yl)-2,2,2-trifluoroethanone
CAS No.:75822-10-5
Molecular Formula:C10H7 F3 O2
Molecular Weight:216.1565896
Hs Code.:2932999099
DSSTox Substance ID:DTXSID30505336
Nikkaji Number:J935.752A
Wikidata:Q82360370
Mol file:75822-10-5.mol

Synonyms:75822-10-5;1-(2,3-dihydrobenzofuran-5-yl)-2,2,2-trifluoroethanone;5-(2,2,2-Trifluoroacetyl)-2,3-dihydrobenzofuran;1-(2,3-Dihydro-1-benzofuran-5-yl)-2,2,2-trifluoroethan-1-one;Ethanone, 1-(2,3-dihydro-5-benzofuranyl)-2,2,2-trifluoro- (9CI);DTXSID30505336;1-(2,3-dihydro-1-benzofuran-5-yl)-2,2,2-trifluoroethanone;AKOS017559136;FS-2026;CS-0268056;EN300-1935768;1-(2,3-Dihydrobenzofuran-5-yl)-2,2,2-trifluoroethan-1-one;5-(2,2,2-trifluoroacetyl)-2,3-dihydrobenzofuran, AldrichCPR

Suppliers and Price of 1-(2,3-Dihydrobenzofuran-5-yl)-2,2,2-trifluoroethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(2,3-Dihydrobenzofuran-5-yl)-2,2,2-trifluoroethanone 95+%
10g
$ 489.00

American Custom Chemicals Corporation
5-(2,2,2-TRIFLUOROACETYL)-2,3-DIHYDROBENZOFURAN 95.00%
5MG
$ 495.65

Total 4 raw suppliers

Chemical Property of 1-(2,3-Dihydrobenzofuran-5-yl)-2,2,2-trifluoroethanone

Chemical Property:

PSA：26.30000
LogP:2.36650
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:216.03981395
Heavy Atom Count:15
Complexity:262

Purity/Quality:

99% ^*data from raw suppliers

1-(2,3-Dihydrobenzofuran-5-yl)-2,2,2-trifluoroethanone 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC2=C1C=C(C=C2)C(=O)C(F)(F)F

Technology Process of 1-(2,3-Dihydrobenzofuran-5-yl)-2,2,2-trifluoroethanone

There total 2 articles about 1-(2,3-Dihydrobenzofuran-5-yl)-2,2,2-trifluoroethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 496-16-2
2.3-dihydrobenzofuran

: 407-25-0
trifluoroacetic anhydride

: 75822-10-5
1-(2,3-dihydrobenzofuran-5-yl)-2,2,2-trifluoroethan-1-one

Guidance literature:: With aluminium trichloride; In carbon disulfide; Heating;

Reference yield:

: 134401-95-9
(2,3-dihydrobenzofuran-5-yl)magnesium bromide

: 407-25-0
trifluoroacetic anhydride

: 75822-10-5
1-(2,3-dihydrobenzofuran-5-yl)-2,2,2-trifluoroethan-1-one

Guidance literature:: at -78 ℃;
DOI:10.1246/bcsj.63.1129

Reference yield: 68.0%

: 68099-99-0
2-phenyl-4-(1-phenylethylidene)oxazol-5(4H)-one

: 75822-10-5
1-(2,3-dihydrobenzofuran-5-yl)-2,2,2-trifluoroethan-1-one

: (R)-N-(6-(2,3-dihydrobenzofuran-5-yl)-2-oxo-4-phenyl-6-(trifluoromethyl)-5,6-dihydro-2H-pyran-3-yl)benzamide

Guidance literature:: With 1-(3,5-bis(trifluoromethyl)phenyl)-3-((S)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)urea; In para-xylene; at 20 ℃; for 120h; enantioselective reaction;
DOI:10.1021/acs.joc.9b03076