1-[3,5-Bis(trifluoromethyl)phenyl]propan-1-ol

Base Information

Chemical Name:1-[3,5-Bis(trifluoromethyl)phenyl]propan-1-ol
CAS No.:742097-70-7
Molecular Formula:C₁₁H₁₀F₆O
Molecular Weight:272.19
Hs Code.:2906290090
European Community (EC) Number:642-619-4
Nikkaji Number:J775.566J
Mol file:742097-70-7.mol

Synonyms:1-[3,5-bis(trifluoromethyl)phenyl]propan-1-ol;742097-70-7;184888-50-4;1-(3,5-Bis(trifluoromethyl)phenyl)propan-1-ol;1-[3,5-Bis(trifluoromethyl)phenyl]propanol;1-[3,5-Bis(trifluoromethyl)phenyl]-1-propanol;1-[3,5-bis-(Trifluoromethyl)phenyl]propan-1-ol;SCHEMBL2394599;MFCD08062371;AKOS005257706;N11941;Benzenemethanol,a-ethyl-3,5-bis(trifluoromethyl)-,(-)-;(-)-| inverted exclamation mark-Ethyl-3,5-bis(trifluoromethyl)benzenemethanol

Suppliers and Price of 1-[3,5-Bis(trifluoromethyl)phenyl]propan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]PROPAN-1-OL 95.00%
1G
$ 721.88

Alfa Aesar
1-[3,5-Bis(trifluoromethyl)phenyl]propanol, 95%
25g
$ 105.00

Alfa Aesar
1-[3,5-Bis(trifluoromethyl)phenyl]propanol, 95%
5g
$ 32.20

Total 7 raw suppliers

Chemical Property of 1-[3,5-Bis(trifluoromethyl)phenyl]propan-1-ol

Chemical Property:

PSA：20.23000
LogP:4.16760
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:272.06358391
Heavy Atom Count:18
Complexity:250

Purity/Quality:

98%min ^*data from raw suppliers

1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]PROPAN-1-OL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O

Technology Process of 1-[3,5-Bis(trifluoromethyl)phenyl]propan-1-ol

There total 6 articles about 1-[3,5-Bis(trifluoromethyl)phenyl]propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 401-95-6
3,5-Bis(trifluoromethyl)benzaldehyde

: 925-90-6
ethylmagnesium bromide

: 184888-50-4,742097-70-7,575488-43-6
1-[3,5-bis(trifluoromethyl)phenyl]propan-1-ol

Guidance literature:: 3,5-Bis(trifluoromethyl)benzaldehyde; ethylmagnesium bromide; In tetrahydrofuran; at 0 ℃; for 0.5h;

With hydrogenchloride; water; In tetrahydrofuran; pH=< 7;

Reference yield: 23.0%

: 85068-34-4
1-[3,5-bis(trifluoromethyl)phenyl]-propan-1-one

: 184888-50-4,742097-70-7,575488-43-6
1-[3,5-bis(trifluoromethyl)phenyl]propan-1-ol

Guidance literature:: With 2-(Aminomethyl)pyridine; bromopentacarbonylmanganese(I); potassium tert-butylate; hydrogen; In tetrahydrofuran; at 120 ℃; for 12h; under 22502.3 Torr; chemoselective reaction; Autoclave;
DOI:10.1016/j.apcata.2021.118280

Reference yield:

: 401-95-6
3,5-Bis(trifluoromethyl)benzaldehyde

: 557-20-0
diethylzinc

: 184888-50-4,742097-70-7,575488-43-6
1-[3,5-bis(trifluoromethyl)phenyl]propan-1-ol

Guidance literature:: 3,5-Bis(trifluoromethyl)benzaldehyde; With (rac)-1-(6-bromopyridin-2-yl)-2,2-dimethylpropan-1-ol; In toluene; at 22 ℃; for 0.166667h; Inert atmosphere;

diethylzinc; In hexane; toluene; at 22 ℃; Inert atmosphere;
DOI:10.1039/d1cc04556c