4-(4'-(1-(methoxycarbonyl)cyclopropyl)-[1,1'-biphenyl]-4-yl)-1-methyl-1H-imidazole-5-carbaldehyde

Base Information

Chemical Name:4-(4'-(1-(methoxycarbonyl)cyclopropyl)-[1,1'-biphenyl]-4-yl)-1-methyl-1H-imidazole-5-carbaldehyde
CAS No.:1443368-78-2
Molecular Formula:C₂₂H₂₀N₂O₃
Molecular Weight:360.412
Hs Code.:

Synonyms:4-(4'-(1-(methoxycarbonyl)cyclopropyl)-[1,1'-biphenyl]-4-yl)-1-methyl-1H-imidazole-5-carbaldehyde

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Chemical Property of 4-(4'-(1-(methoxycarbonyl)cyclopropyl)-[1,1'-biphenyl]-4-yl)-1-methyl-1H-imidazole-5-carbaldehyde

Chemical Property:

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Technology Process of 4-(4'-(1-(methoxycarbonyl)cyclopropyl)-[1,1'-biphenyl]-4-yl)-1-methyl-1H-imidazole-5-carbaldehyde

There total 3 articles about 4-(4'-(1-(methoxycarbonyl)cyclopropyl)-[1,1'-biphenyl]-4-yl)-1-methyl-1H-imidazole-5-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1217501-08-0
(4-(1-(methoxycarbonyl)cyclopropyl)phenyl)boronic acid

: 1443368-77-1
4-(4-bromophenyl)-1-methyl-1H-imidazole-5-carbaldehyde

: 1443368-78-2
4-(4'-(1-(methoxycarbonyl)cyclopropyl)-[1,1'-biphenyl]-4-yl)-1-methyl-1H-imidazole-5-carbaldehyde

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,4-dioxane; at 80 ℃; Inert atmosphere;

Reference yield:

: 5467-74-3
4-Bromophenylboronic acid

: 1443368-78-2
4-(4'-(1-(methoxycarbonyl)cyclopropyl)-[1,1'-biphenyl]-4-yl)-1-methyl-1H-imidazole-5-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / 1,4-dioxane / 80 °C / Inert atmosphere

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / 1,4-dioxane / 80 °C / Inert atmosphere

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,4-dioxane;

Reference yield:

: 39021-62-0
1-methylimidazole-5-carbaldehyde

: 1443368-78-2
4-(4'-(1-(methoxycarbonyl)cyclopropyl)-[1,1'-biphenyl]-4-yl)-1-methyl-1H-imidazole-5-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / 1,4-dioxane / 80 °C / Inert atmosphere

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / 1,4-dioxane / 80 °C / Inert atmosphere

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,4-dioxane;