(R)-N-(3-(3-(4-chlorophenyl)guanidino)propyl)-2,4-dihydroxy-3,3-dimethylbutanamide

Base Information

Chemical Name:(R)-N-(3-(3-(4-chlorophenyl)guanidino)propyl)-2,4-dihydroxy-3,3-dimethylbutanamide
CAS No.:1610839-70-7
Molecular Formula:C₁₆H₂₅ClN₄O₃
Molecular Weight:356.852
Hs Code.:

Synonyms:(R)-N-(3-(3-(4-chlorophenyl)guanidino)propyl)-2,4-dihydroxy-3,3-dimethylbutanamide

Suppliers and Price of (R)-N-(3-(3-(4-chlorophenyl)guanidino)propyl)-2,4-dihydroxy-3,3-dimethylbutanamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-N-(3-(3-(4-chlorophenyl)guanidino)propyl)-2,4-dihydroxy-3,3-dimethylbutanamide

Chemical Property:

Purity/Quality:

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Technology Process of (R)-N-(3-(3-(4-chlorophenyl)guanidino)propyl)-2,4-dihydroxy-3,3-dimethylbutanamide

There total 4 articles about (R)-N-(3-(3-(4-chlorophenyl)guanidino)propyl)-2,4-dihydroxy-3,3-dimethylbutanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₀H₁₅ClN₄

: 599-04-2
(R)-Pantolacton

: 1610839-70-7
(R)-N-(3-(3-(4-chlorophenyl)guanidino)propyl)-2,4-dihydroxy-3,3-dimethylbutanamide

Guidance literature:: With triethylamine; In ethanol; at 75 ℃; for 24h;
DOI:10.1016/j.bmc.2014.04.030

Reference yield:

: 1610839-79-6
tert-butyl 3-(3-(4-chlorophenyl)guanidino)propylcarbamate

: 1610839-70-7
(R)-N-(3-(3-(4-chlorophenyl)guanidino)propyl)-2,4-dihydroxy-3,3-dimethylbutanamide

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / 1 h / 20 °C

2: triethylamine / ethanol / 24 h / 75 °C

With triethylamine; trifluoroacetic acid; In ethanol;
DOI:10.1016/j.bmc.2014.04.030

Reference yield:

: 106-47-8
4-chloro-aniline

: 1610839-70-7
(R)-N-(3-(3-(4-chlorophenyl)guanidino)propyl)-2,4-dihydroxy-3,3-dimethylbutanamide

Guidance literature:: Multi-step reaction with 4 steps

1: tetrahydrofuran / 20 °C

2: tetrahydrofuran / 24 h / Reflux

3: trifluoroacetic acid / 1 h / 20 °C

4: triethylamine / ethanol / 24 h / 75 °C

With triethylamine; trifluoroacetic acid; In tetrahydrofuran; ethanol;
DOI:10.1016/j.bmc.2014.04.030