Bicyclo[2.2.1]heptan-2-ol, 1,3,3-trimethyl-2-(2-propenyl)-, (1S,2R,4R)- (9CI)

Base Information

• Chemical Name: Bicyclo[2.2.1]heptan-2-ol, 1,3,3-trimethyl-2-(2-propenyl)-, (1S,2R,4R)- (9CI)
• CAS No.: 740817-73-6
• Molecular Formula: C₁₃H₂₂O
• Molecular Weight: 194.317
• Mol file: 740817-73-6.mol

Synonyms:Bicyclo[2.2.1]heptan-2-ol,1,3,3-trimethyl-2-(2-propenyl)-, (1S,2R,4R)- (9CI)

Chemical Property of Bicyclo[2.2.1]heptan-2-ol, 1,3,3-trimethyl-2-(2-propenyl)-, (1S,2R,4R)- (9CI)

Chemical Property:

• Boiling Point: 237.1±9.0 °C(Predicted)
• PKA: 15.24±0.60(Predicted)
• PSA: 20.23000
• Density: 0.957±0.06 g/cm3(Predicted)
• LogP: 3.13980

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Bicyclo[2.2.1]heptan-2-ol, 1,3,3-trimethyl-2-(2-propenyl)-, (1S,2R,4R)- (9CI)

There total 6 articles about Bicyclo[2.2.1]heptan-2-ol, 1,3,3-trimethyl-2-(2-propenyl)-, (1S,2R,4R)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

(1R)-fenchone (7787-20-4,126-21-6) + allylmagnesium bromide (2622-05-1) → (1R,2R)-2-endo-hydroxy-2-exo-allyl-1,3,3-trimethylbicyclo<2.2.1>heptane (740817-73-6)

Guidance literature:

In tetrahydrofuran; at -20 - 20 ℃; for 1.5h;

DOI:10.1016/0040-4020(95)01005-X

Reference yield: 90.0%

(1R)-fenchone (7787-20-4,126-21-6) → (1R)-1,3,3-trimethyl-2-(prop-2-enyl)bicyclo[2.2.1]heptan-2-ol (740817-73-6)

Guidance literature:

In tetrahydrofuran; at -50 ℃;

DOI:10.1016/S0957-4166(00)86259-X

Reference yield:

allyl iodid (556-56-9) + fenchone (4695-62-9,126-21-6) → Allylfenchylalkohol (91975-38-1,740817-73-6)

Guidance literature:

With diethyl ether; zinc; allylfenchyl alcohol;

upstream raw materials:

allyl iodid

fenchone

1,3,3-trimethyl-2-norbornanone

allylmagnesium bromide