2,2-DiMethyl-propanoic Acid [2-[[(2-AMino-5-thiazolyl)carbonyl]aMino]-3-chlorophenyl]Methyl Ester

Base Information

Chemical Name:2,2-DiMethyl-propanoic Acid [2-[[(2-AMino-5-thiazolyl)carbonyl]aMino]-3-chlorophenyl]Methyl Ester
CAS No.:910297-69-7
Molecular Formula:C₁₆H₁₈ClN₃O₃S
Molecular Weight:367.856
Hs Code.:
Mol file:910297-69-7.mol

Synonyms:2-(2-aminothiazole-5-carboxamido)-3-chlorobenzyl pivalate

Suppliers and Price of 2,2-DiMethyl-propanoic Acid [2-[[(2-AMino-5-thiazolyl)carbonyl]aMino]-3-chlorophenyl]Methyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,2-Dimethyl-propanoicAcid[2-[[(2-Amino-5-thiazolyl)carbonyl]amino]-3-chlorophenyl]methylEster
2.5mg
$ 155.00

Medical Isotopes, Inc.
2,2-Dimethyl-propanoicAcid[2-[[(2-Amino-5-thiazolyl)carbonyl]amino]-3-chlorophenyl]methylEster
2.5 mg
$ 640.00

Total 0 raw suppliers

Chemical Property of 2,2-DiMethyl-propanoic Acid [2-[[(2-AMino-5-thiazolyl)carbonyl]aMino]-3-chlorophenyl]Methyl Ester

Chemical Property:

Melting Point:194-197°C
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:: 2,2-Dimethyl-propanoicAcid[2-[[(2-Amino-5-thiazolyl)carbonyl]amino]-3-chlorophenyl]methylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 2,2-DiMethyl-propanoic Acid [2-[[(2-AMino-5-thiazolyl)carbonyl]aMino]-3-chlorophenyl]Methyl Ester is an intermediate in the preparation of Dasatinib metabolite, used in the treatment of cancers and immune diseases.

Technology Process of 2,2-DiMethyl-propanoic Acid [2-[[(2-AMino-5-thiazolyl)carbonyl]aMino]-3-chlorophenyl]Methyl Ester

There total 1 articles about 2,2-DiMethyl-propanoic Acid [2-[[(2-AMino-5-thiazolyl)carbonyl]aMino]-3-chlorophenyl]Methyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 910298-41-8
3-chloro-2-(2-(tritylamino)thiazole-5-carboxamido)benzyl pivalate

: 910297-69-7
2-(2-aminothiazole-5-carboxamido)-3-chlorobenzyl pivalate

Guidance literature:: With formic acid; ethanol; water; for 24h; Heating / reflux;

Reference yield: 66.0%

: 1780-26-3
2,4-dichloro-2-methylpyrimidine

: 910297-69-7
2-(2-aminothiazole-5-carboxamido)-3-chlorobenzyl pivalate

: 910297-70-0
3-chloro-2-(2-(6-chloro-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamido)benzyl pivalate

Guidance literature:: 2,4-dichloro-2-methylpyrimidine; 2-(2-aminothiazole-5-carboxamido)-3-chlorobenzyl pivalate; With sodium t-butanolate; In tetrahydrofuran; at 10 - 18 ℃; for 1.5h;

With hydrogenchloride; In tetrahydrofuran; water; at 0 ℃;