910297-70-0 Usage
Uses
Used in Pharmaceutical Industry:
Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro-O-pivalate Dasatinib is used as an intermediate in the preparation of Dasatinib metabolite for the treatment of cancers. It plays a crucial role in the development of pharmaceutical formulations that target specific tyrosine kinases, which are often implicated in the growth and progression of various malignancies.
Used in Immunology Research:
Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro-O-pivalate Dasatinib is also used as a research tool in immunology, where it can help scientists understand the role of tyrosine kinases in immune cell signaling and the regulation of immune responses. This knowledge can contribute to the development of novel therapeutic strategies for immune-related diseases.
Used in Drug Development:
In the field of drug development, Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro-O-pivalate Dasatinib serves as a valuable compound for the synthesis of new and improved Dasatinib analogs. These analogs may exhibit enhanced potency, selectivity, or reduced side effects, making them more effective in the treatment of cancers and immune diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 910297-70-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,0,2,9 and 7 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 910297-70:
(8*9)+(7*1)+(6*0)+(5*2)+(4*9)+(3*7)+(2*7)+(1*0)=160
160 % 10 = 0
So 910297-70-0 is a valid CAS Registry Number.
910297-70-0Relevant academic research and scientific papers
PROCESS FOR PREPARING N-(2-CHLORO-6-METHYLPHENYL)-2-[[6-[4-(2-HYDROXYETHYL)-1-PIPERAZINYL]-2-METHYL-4-PYRIMIDINYL]AMINO] -5-THIAZOLECARBOXAMIDE AND RELATED METABOLITES THEREOF
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Page/Page column 24; 26, (2010/11/28)
The present invention is directed to process for the preparation of metabolites as well as the parent compound of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl] amino]-5-thiazolecarboxamide, the compound of formula (I).
'N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamides metabolites
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Page/Page column 34, (2008/06/13)
The present invention is directed to metabolites of ′N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide, the compound of formula (I), pharmaceutical compositions thereof, and to methods
