2'-O-Methyladenosine

Base Information

Chemical Name:2'-O-Methyladenosine
CAS No.:2140-79-6
Molecular Formula:C11H15N5O4
Molecular Weight:281.271
Hs Code.:29349990
UNII:02YX82IHZ5
DSSTox Substance ID:DTXSID50175671
Nikkaji Number:J109.807A
Wikidata:Q15632794
Pharos Ligand ID:WC856N8FWHG9
Metabolomics Workbench ID:38514
ChEMBL ID:CHEMBL73237
Mol file:2140-79-6.mol

Synonyms:2'-O-methyladenosine;2'-O-methyladenosine, (alpha-D-arabino)-isomer;2'-O-methyladenosine, (beta-D-arabino)-isomer

Suppliers and Price of 2'-O-Methyladenosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2'-O-Methyladenosine 98%
1g
$ 165.00

Matrix Scientific
2'-O-Methyladenosine 98%
250mg
$ 85.00

Medical Isotopes, Inc.
2?-O-Methyl-adenosine
50 mg
$ 1400.00

Sigma-Aldrich
2′-O-Methyladenosine
5mg
$ 328.00

TCI Chemical
2'-O-Methyladenosine >98.0%(HPLC)(T)
1g
$ 221.00

TRC
2''-O-MethylAdenosine
10mg
$ 75.00

Crysdot
(2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol 98%
10g
$ 628.00

Crysdot
(2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol 98%
5g
$ 400.00

Crysdot
(2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol 98%
1g
$ 130.00

ChemScene
2'-O-Methyladenosine ≥98.0%
1g
$ 80.00

Total 84 raw suppliers

Chemical Property of 2'-O-Methyladenosine

Chemical Property:

Appearance/Colour:White solid
Melting Point:200-202 °C
Boiling Point:623.759 °C at 760 mmHg
PKA:13.13±0.70(Predicted)
Flash Point:331.038 °C
PSA：128.54000
Density:1.843 g/cm³
LogP:-0.74470
Storage Temp.:−20°C
Solubility.:DMSO (Slightly), Methanol (Slightly, Heated, Sonicated), Water (Slightly)
Water Solubility.:Soluble in water.
XLogP3:-0.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:281.11240398
Heavy Atom Count:20
Complexity:349

Purity/Quality:

98%, ^*data from raw suppliers

2'-O-Methyladenosine 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:COC1C(C(OC1N2C=NC3=C(N=CN=C32)N)CO)O
Isomeric SMILES:CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)N)CO)O
Description 2'-O-Methyladenosine (Cordysinin B) is a member of the class of adenosines that is adenosine in which the hydroxy group at position 2' is replaced by a methoxy group. It has been isolated from the mycelia of Cordyceps sinensis. It has a role as a fungal metabolite. It is a member of adenosines and an ether. It derives from an adenosine. analogue with antiviral properties, starting material for 2'-O'-methyl nucleotides. Potential metabolite of 2'-O-Me-cAMP.
Uses 2'-O-Methyladenosine is an analog of adenosine used to prepare nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase. Adenosine analog.

Technology Process of 2'-O-Methyladenosine

There total 35 articles about 2'-O-Methyladenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 57817-83-1
N⁶,O^2'-methyladenosine

: 2140-79-6
2'-O-methyl adenosine

Guidance literature:: With manganese(IV) oxide; C₁₇H₂₀N₄O₉P^(1-)*Na⁽¹⁺⁾; oxygen; In water; acetonitrile; at 20 ℃; for 7h; under 760.051 Torr; chemoselective reaction; Irradiation;
DOI:10.1002/anie.201900901

Reference yield: 37.0%

: 17287-03-5
trimethylsulphonium hydroxide

: 58-61-7
adenosine

: 60037-52-7
N⁶,O^3'-methyladenosine

: 57817-83-1
N⁶,O^2'-methyladenosine

: 2140-79-6
2'-O-methyl adenosine

: 10300-22-8
3'-O-methyladenosine

Guidance literature:: With copper acetylacetonate; In N,N-dimethyl-formamide; at 70 ℃; for 1h; Further byproducts given;
DOI:10.1021/jo01307a026