(S)-Methyl 4-((3-(((tert-butoxycarbonyl)amino)(phenyl)methyl)phenoxy)-methyl)benzoate

Base Information

Chemical Name:(S)-Methyl 4-((3-(((tert-butoxycarbonyl)amino)(phenyl)methyl)phenoxy)-methyl)benzoate
CAS No.:1416069-96-9
Molecular Formula:C₂₇H₂₉NO₅
Molecular Weight:447.531
Hs Code.:

Synonyms:(S)-Methyl 4-((3-(((tert-butoxycarbonyl)amino)(phenyl)methyl)phenoxy)-methyl)benzoate

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Chemical Property of (S)-Methyl 4-((3-(((tert-butoxycarbonyl)amino)(phenyl)methyl)phenoxy)-methyl)benzoate

Chemical Property:

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Technology Process of (S)-Methyl 4-((3-(((tert-butoxycarbonyl)amino)(phenyl)methyl)phenoxy)-methyl)benzoate

There total 7 articles about (S)-Methyl 4-((3-(((tert-butoxycarbonyl)amino)(phenyl)methyl)phenoxy)-methyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 2417-72-3
Methyl 4-(bromomethyl)benzoate

: 1416069-62-9
(S)-tert-butyl ((3-hydroxyphenyl)(phenyl)methyl)carbamate

: 1416069-96-9
(S)-Methyl 4-((3-(((tert-butoxycarbonyl)amino)(phenyl)methyl)phenoxy)-methyl)benzoate

Guidance literature:: With potassium carbonate; In acetonitrile; at 20 ℃; for 16h;

Reference yield:

: 2417-72-3
Methyl 4-(bromomethyl)benzoate

: tert-Butyl((3-hydroxyphenyl)(phenyl)methyl)carbamate

: 1416069-96-9
(S)-Methyl 4-((3-(((tert-butoxycarbonyl)amino)(phenyl)methyl)phenoxy)-methyl)benzoate

Guidance literature:: With potassium carbonate; In acetonitrile;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1416069-96-9
(S)-Methyl 4-((3-(((tert-butoxycarbonyl)amino)(phenyl)methyl)phenoxy)-methyl)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-ethyl-N,N-diisopropylamine / dichloromethane-d2 / 18 h / 0 - 20 °C

1.2: 16 h / 20 °C

2.1: potassium carbonate / acetonitrile / 16 h / 20 °C

With potassium carbonate; N-ethyl-N,N-diisopropylamine; In dichloromethane-d2; acetonitrile;