2-(Ethoxymethylidene)-3-oxo-N-[4-(trifluoromethyl)phenyl]butanamide

Base Information

Chemical Name:2-(Ethoxymethylidene)-3-oxo-N-[4-(trifluoromethyl)phenyl]butanamide
CAS No.:75706-11-5
Molecular Formula:C14H14 F3 N O3
Molecular Weight:301.265
Hs Code.:
DSSTox Substance ID:DTXSID10698452
Mol file:75706-11-5.mol

Synonyms:75706-11-5;2-(Ethoxymethylidene)-3-oxo-N-[4-(trifluoromethyl)phenyl]butanamide;DTXSID10698452;N-[4-(Trifluoromethyl)phenyl]-2-(ethoxymethylene)acetoacetamide;N-[4-(Trifluoromethyl)phenyl]-2-(ethoxymethylene)-acetoacetamide

Suppliers and Price of 2-(Ethoxymethylidene)-3-oxo-N-[4-(trifluoromethyl)phenyl]butanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-(Ethoxymethylidene)-3-oxo-N-[4-(trifluoromethyl)phenyl]butanamide

Chemical Property:

Vapor Pressure:2.92E-08mmHg at 25°C
Refractive Index:1.509
Boiling Point:449.2°C at 760 mmHg
Flash Point:225.5°C
PSA：55.40000
Density:1.279g/cm³
LogP:3.22630
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:301.09257779
Heavy Atom Count:21
Complexity:410

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC=C(C(=O)C)C(=O)NC1=CC=C(C=C1)C(F)(F)F

Technology Process of 2-(Ethoxymethylidene)-3-oxo-N-[4-(trifluoromethyl)phenyl]butanamide

There total 2 articles about 2-(Ethoxymethylidene)-3-oxo-N-[4-(trifluoromethyl)phenyl]butanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 351-87-1
N-(4-trifluoromethylphenyl)-2-acetylacetamide

: 122-51-0
orthoformic acid triethyl ester

: 75706-11-5
2-ethoxymethyleneacetoacetyl-(4-trifluoromethyl)aniline

Guidance literature:: With acetic anhydride; Heating;
DOI:10.1016/S0960-894X(98)00501-0

Reference yield:

: 455-14-1
4-trifluoromethylphenylamine

: 75706-11-5
2-ethoxymethyleneacetoacetyl-(4-trifluoromethyl)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / 60 °C

2: Ac₂O / Heating

With acetic anhydride; In toluene;
DOI:10.1016/S0960-894X(98)00501-0