(R)-3-(2-(hydroxydiphenylmethyl)pyrrolidin-1-ylsulfonyl)propyl acetate

Base Information

Chemical Name:(R)-3-(2-(hydroxydiphenylmethyl)pyrrolidin-1-ylsulfonyl)propyl acetate
CAS No.:1370293-23-4
Molecular Formula:C₂₂H₂₅F₂NO₅S
Molecular Weight:453.507
Hs Code.:

Synonyms:(R)-3-(2-(hydroxydiphenylmethyl)pyrrolidin-1-ylsulfonyl)propyl acetate

Suppliers and Price of (R)-3-(2-(hydroxydiphenylmethyl)pyrrolidin-1-ylsulfonyl)propyl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-3-(2-(hydroxydiphenylmethyl)pyrrolidin-1-ylsulfonyl)propyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-3-(2-(hydroxydiphenylmethyl)pyrrolidin-1-ylsulfonyl)propyl acetate

There total 4 articles about (R)-3-(2-(hydroxydiphenylmethyl)pyrrolidin-1-ylsulfonyl)propyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 1370293-17-6
(R)-(1-(3-chloropropylsulfonyl)pyrrolidin-2-yl)bis(3-fluorophenyl)methanol

: 127-09-3
sodium acetate

: 1370293-23-4
(R)-3-(2-(hydroxydiphenylmethyl)pyrrolidin-1-ylsulfonyl)propyl acetate

Guidance literature:: With sodium iodide; In N,N-dimethyl-formamide; at 90 ℃; for 12h;
DOI:10.1021/jm201627n

Reference yield:

: 1204659-63-1
(S)-bis(3-fluorophenyl)(pyrrolidin-2-yl)methanol

: 1370293-23-4
(R)-3-(2-(hydroxydiphenylmethyl)pyrrolidin-1-ylsulfonyl)propyl acetate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 2 h / 0 - 20 °C

2: sodium iodide / N,N-dimethyl-formamide / 12 h / 90 °C

With triethylamine; sodium iodide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm201627n

Reference yield:

: 1370292-84-4
(S)-ethyl 2-(bis(3-fluorophenyl)(hydroxy)methyl)pyrrolidine-1-carboxylate

: 1370293-23-4
(R)-3-(2-(hydroxydiphenylmethyl)pyrrolidin-1-ylsulfonyl)propyl acetate

Guidance literature:: Multi-step reaction with 3 steps

1: methanol; potassium hydroxide / 12 h / Reflux

2: triethylamine / dichloromethane / 2 h / 0 - 20 °C

3: sodium iodide / N,N-dimethyl-formamide / 12 h / 90 °C

With methanol; triethylamine; sodium iodide; potassium hydroxide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm201627n