Methyl 4-amino-1,2-thiazole-3-carboxylate

Base Information

Chemical Name:Methyl 4-amino-1,2-thiazole-3-carboxylate
CAS No.:734492-43-4
Molecular Formula:C5H6 N2 O2 S
Molecular Weight:158.181
Hs Code.:
European Community (EC) Number:831-081-8
DSSTox Substance ID:DTXSID10547754
Wikidata:Q82426186
Mol file:734492-43-4.mol

Synonyms:734492-43-4;methyl 4-amino-1,2-thiazole-3-carboxylate;methyl 4-aminoisothiazole-3-carboxylate;methyl4-aminoisothiazole-3-carboxylate;SCHEMBL3614725;DTXSID10547754;WAZIIMXTDNUMIX-UHFFFAOYSA-N;MFCD13175091;AKOS023809448;AT21157;CCG-321174;EN300-103167;4-amino-isothiazole-3-carboxylic acid methyl ester;Z1255459041

Suppliers and Price of Methyl 4-amino-1,2-thiazole-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
methyl4-amino-1,2-thiazole-3-carboxylate
10mg
$ 45.00

AK Scientific
Methyl4-amino-1,2-thiazole-3-carboxylate
5g
$ 3470.00

AK Scientific
Methyl4-amino-1,2-thiazole-3-carboxylate
2.5g
$ 2389.00

Total 7 raw suppliers

Chemical Property of Methyl 4-amino-1,2-thiazole-3-carboxylate

Chemical Property:

Boiling Point:198.0±33.0 °C(Predicted)
PKA:1.89±0.10(Predicted)
PSA：93.45000
Density:1.408±0.06 g/cm3(Predicted)
LogP:1.09310
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:158.01499861
Heavy Atom Count:10
Complexity:142

Purity/Quality:

97% ^*data from raw suppliers

methyl4-amino-1,2-thiazole-3-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=NSC=C1N

Technology Process of Methyl 4-amino-1,2-thiazole-3-carboxylate

There total 4 articles about Methyl 4-amino-1,2-thiazole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 67-56-1
methanol

: 462067-90-9
4-aminoisothiazole-3-carboxylic acid

: 734492-43-4
methyl 4-amino-1,2-thiazole-3-carboxylate

Guidance literature:: With thionyl chloride; at 20 ℃; for 20h;

Reference yield: 79.0%

: 734492-43-4
methyl 4-amino-1,2-thiazole-3-carboxylate

Guidance literature:

Reference yield: 66.0%

: C₆H₇N₃O₃S

: 734492-43-4
methyl 4-amino-1,2-thiazole-3-carboxylate

Guidance literature:: C₆H₇N₃O₃S; With hydrogenchloride; In water; at 120 ℃; for 2h; Reflux;

With sulfuric acid; In methanol; water; for 12h; Reflux;
DOI:10.1021/jacs.5b10420