[1,1'-Biphenyl]-4-propanal

Base Information

• Chemical Name: [1,1'-Biphenyl]-4-propanal
• CAS No.: 75677-09-7
• Molecular Formula: C15H14 O
• Molecular Weight: 210.276
• European Community (EC) Number: 870-550-1
• DSSTox Substance ID: DTXSID30698893
• Nikkaji Number: J2.798.672B
• Wikidata: Q82629456
• Mol file: 75677-09-7.mol

Synonyms:[1,1'-Biphenyl]-4-propanal;75677-09-7;3-(4-phenylphenyl)propanal;3-([1,1'-Biphenyl]-4-yl)propanal;3-{[1,1'-BIPHENYL]-4-YL}PROPANAL;3-BIPHENYL-4-YL-PROPIONALDEHYDE;3-(Biphenyl-4-yl)propanal;SCHEMBL6641300;DTXSID30698893;QGJDVSWMEVFRCW-UHFFFAOYSA-N;EN300-211045;Z1263604106

Chemical Property of [1,1'-Biphenyl]-4-propanal

Chemical Property:

• Vapor Pressure: 7.76E-05mmHg at 25°C
• Refractive Index: 1.561
• Boiling Point: 342°C at 760 mmHg
• Flash Point: 178.8°C
• PSA: 17.07000
• Density: 1.044g/cm³
• LogP: 3.48510
• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 210.104465066
• Heavy Atom Count: 16
• Complexity: 198

Purity/Quality:

97% ^*data from raw suppliers

3-(4-phenylphenyl)propanal ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)CCC=O

Technology Process of [1,1'-Biphenyl]-4-propanal

There total 14 articles about [1,1'-Biphenyl]-4-propanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

ethyl 3-([1,1′-biphenyl]-4-yl)propanoate (40796-00-7) → 3-([1,1′-biphenyl]-4-yl)propanal (75677-09-7)

Guidance literature:

With diisobutylaluminium hydride; In hexane; dichloromethane; at -78 ℃; for 2h;

DOI:10.1021/jm701210y

Reference yield: 85.0%

4-(3-Hydroxypropyl)[1,1'-biphenyl] (78733-60-5) → 3-([1,1′-biphenyl]-4-yl)propanal (75677-09-7)

Guidance literature:

With 1-methyl-1H-imidazole; [2,2]bipyridinyl; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; tetrakis(acetonitrile)copper(I) trifluoromethanesulfonate; In acetonitrile; at 20 ℃;

DOI:10.1021/jacs.0c01330

Reference yield: 77.0%

4-iodo-biphenyl (1591-31-7) + allyl alcohol (107-18-6) → 3-([1,1′-biphenyl]-4-yl)propanal (75677-09-7)

Guidance literature:

With tetrabutylammomium bromide; palladium diacetate; sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 50 ℃; Inert atmosphere; Schlenk technique;

DOI:10.1002/anie.202011996

upstream raw materials:

carbon monoxide

p-vinylbiphenyl

ethyl 3-([1,1′-biphenyl]-4-yl)propanoate

4-Phenylbenzaldehyde

Downstream raw materials:

3-([1,1'-biphenyl]-4-yl)acrylaldehyde

(E)-3-([1,1′-biphenyl]-4-yl)acrylaldehyde

5H-r,7-(p-biphenylyl)-cis-4-bromo-cis-3-hydroxy-trans-3-methylheptan-5-olide