methyl 6-benzyl-5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylate hydrochloride

Base Information

Chemical Name:methyl 6-benzyl-5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylate hydrochloride
CAS No.:1361381-49-8
Molecular Formula:C₁₇H₁₈N₂O₂*ClH
Molecular Weight:318.803
Hs Code.:

Synonyms:methyl 6-benzyl-5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylate hydrochloride

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Chemical Property of methyl 6-benzyl-5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylate hydrochloride

Chemical Property:

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Technology Process of methyl 6-benzyl-5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylate hydrochloride

There total 1 articles about methyl 6-benzyl-5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 67-56-1
methanol

: 1160995-15-2
6-benzyl-5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylic acid

: 1361381-49-8
methyl 6-benzyl-5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylate hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 80 ℃; for 13h; Sealed tube;

Reference yield:

: 1361381-49-8
methyl 6-benzyl-5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylate hydrochloride

: 1361381-52-3
methyl 6-(benzylcarbamoyl)-5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen / palladium(II) hydroxide / methanol / 13 h / 20 °C / 760.05 Torr / Inert atmosphere

2: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 13 h / 20 °C

With hydrogen; N-ethyl-N,N-diisopropylamine; palladium(II) hydroxide; In methanol; N,N-dimethyl-formamide;

Reference yield:

: 1361381-49-8
methyl 6-benzyl-5,6,7,8-tetrahydro-1,6-naphthyridine-2-carboxylate hydrochloride

: 1361380-94-0
N₆-benzyl-N₂-hydroxy-7,8-dihydro-1,6-naphthyridine-2,6(5H)-dicarboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogen / palladium(II) hydroxide / methanol / 13 h / 20 °C / 760.05 Torr / Inert atmosphere

2: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 13 h / 20 °C

3: hydroxylamine potassium salt / methanol / 13 h / 20 °C

With hydroxylamine potassium salt; hydrogen; N-ethyl-N,N-diisopropylamine; palladium(II) hydroxide; In methanol; N,N-dimethyl-formamide;