Methyl (E)-2-<<(2,4,6-trimethylbenzoyl)oxy>methyl>-2-pentenoate

Base Information

• Chemical Name: Methyl (E)-2-<<(2,4,6-trimethylbenzoyl)oxy>methyl>-2-pentenoate
• CAS No.: 153996-36-2
• Molecular Formula: C₁₇H₂₂O₄
• Molecular Weight: 290.359
• Mol file: 153996-36-2.mol

Synonyms:Methyl (E)-2-<<(2,4,6-trimethylbenzoyl)oxy>methyl>-2-pentenoate

Chemical Property of Methyl (E)-2-<<(2,4,6-trimethylbenzoyl)oxy>methyl>-2-pentenoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methyl (E)-2-<<(2,4,6-trimethylbenzoyl)oxy>methyl>-2-pentenoate

There total 2 articles about Methyl (E)-2-<<(2,4,6-trimethylbenzoyl)oxy>methyl>-2-pentenoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

mesitylenecarboxylic acid (480-63-7) + 3-hydroxy-2-methylene-pentanoic acid methyl ester (133181-02-9,18052-21-6) → Methyl (E)-2-<<(2,4,6-trimethylbenzoyl)oxy>methyl>-2-pentenoate (153996-36-2) + 2,4,6-Trimethyl-benzoic acid 1-ethyl-2-methoxycarbonyl-allyl ester

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 0 ℃; for 0.25h; Yields of byproduct given;

DOI:10.1021/jo00126a046

Reference yield:

mesitylenecarboxylic acid (480-63-7) + 3-hydroxy-2-methylene-pentanoic acid methyl ester (133181-02-9,18052-21-6) → Methyl (E)-2-<<(2,4,6-trimethylbenzoyl)oxy>methyl>-2-pentenoate (153996-36-2) + methyl (E)-2-<<(4-nitrobenzoyl)oxy>methyl>-2-pentenoate (153996-35-1)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 0 ℃; for 0.25h; Yield given. Yields of byproduct given;

DOI:10.1016/S0040-4039(00)91807-0

Reference yield: 84.0%

Methyl (E)-2-<<(2,4,6-trimethylbenzoyl)oxy>methyl>-2-pentenoate (153996-36-2) → 2,4,6-Trimethyl-benzoic acid (Z)-2-hydroxymethyl-pent-2-enyl ester (171288-99-6)

Guidance literature:

With diisobutylaluminium hydride; In hexane; dichloromethane; at -78 ℃;

DOI:10.1021/jo00126a046

upstream raw materials:

mesitylenecarboxylic acid

3-hydroxy-2-methylene-pentanoic acid methyl ester

Downstream raw materials:

2,4,6-Trimethyl-benzoic acid (Z)-2-hydroxymethyl-pent-2-enyl ester

2,4,6-Trimethyl-benzoic acid (E)-2-triisopropylsilanyloxymethyl-pent-2-enyl ester