(S,S)-γ-amino-β-hydroxy-N-<2-(4-morpholinyl)ethyl>cyclohexane pentanamide

Base Information

Chemical Name:(S,S)-γ-amino-β-hydroxy-N-<2-(4-morpholinyl)ethyl>cyclohexane pentanamide
CAS No.:124278-65-5
Molecular Formula:C₁₇H₃₃N₃O₃
Molecular Weight:327.467
Hs Code.:

Synonyms:(S,S)-γ-amino-β-hydroxy-N-<2-(4-morpholinyl)ethyl>cyclohexane pentanamide

Suppliers and Price of (S,S)-γ-amino-β-hydroxy-N-<2-(4-morpholinyl)ethyl>cyclohexane pentanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S,S)-γ-amino-β-hydroxy-N-<2-(4-morpholinyl)ethyl>cyclohexane pentanamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S,S)-γ-amino-β-hydroxy-N-<2-(4-morpholinyl)ethyl>cyclohexane pentanamide

There total 9 articles about (S,S)-γ-amino-β-hydroxy-N-<2-(4-morpholinyl)ethyl>cyclohexane pentanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 124278-65-5
(S,S)-γ-amino-β-hydroxy-N-<2-(4-morpholinyl)ethyl>cyclohexane pentanamide

Guidance literature:: Multi-step reaction with 6 steps

1: 1) N,N'-carbonyldiimidazole / 1) tetrahydrofuran, 30 min, 2) tetrahydrofuran, dimethyl sulfoxide, 4h, room temp.

2: 97 percent / H₂ / RuBr₂<(R)-binap> / ethanol / 145 h / 20 °C / 76000.1 Torr

3: 96 percent / aq. potassium hydroxide / dioxane / 8 h / 0 °C

4: H₂ / 5percent Rh-Al₂O₃ / ethanol / 16 h / 3040 - 3800 Torr

5: 96 percent / DEPC, triethylamine / tetrahydrofuran / 6 h / 0 °C

6: 4N HCl / dioxane / 0.5 h / Ambient temperature

With hydrogenchloride; potassium hydroxide; hydrogen; triethylamine; diethyl dicarbonate; 1,1'-carbonyldiimidazole; [(R)-BINAP]RuBr₂; rhodium on alumina; In tetrahydrofuran; 1,4-dioxane; ethanol;
DOI:10.1248/cpb.38.103

Reference yield:

: 72155-48-7
(3S,4S)-4-tert-butoxycarbonylamino-3-hydroxy-5-phenylpentanoic acid

: 124278-65-5
(S,S)-γ-amino-β-hydroxy-N-<2-(4-morpholinyl)ethyl>cyclohexane pentanamide

Guidance literature:: Multi-step reaction with 3 steps

1: H₂ / 5percent Rh-Al₂O₃ / ethanol / 16 h / 3040 - 3800 Torr

2: 96 percent / DEPC, triethylamine / tetrahydrofuran / 6 h / 0 °C

3: 4N HCl / dioxane / 0.5 h / Ambient temperature

With hydrogenchloride; hydrogen; triethylamine; diethyl dicarbonate; rhodium on alumina; In tetrahydrofuran; 1,4-dioxane; ethanol;
DOI:10.1248/cpb.38.103

Reference yield:

: 72155-46-5
(3S,4S)-4-(N-tert-butoxycarbonyl)amino-3-hydroxy-5-phenylpentanoic acid ethyl ester

: 124278-65-5
(S,S)-γ-amino-β-hydroxy-N-<2-(4-morpholinyl)ethyl>cyclohexane pentanamide

Guidance literature:: Multi-step reaction with 4 steps

1: 96 percent / aq. potassium hydroxide / dioxane / 8 h / 0 °C

2: H₂ / 5percent Rh-Al₂O₃ / ethanol / 16 h / 3040 - 3800 Torr

3: 96 percent / DEPC, triethylamine / tetrahydrofuran / 6 h / 0 °C

4: 4N HCl / dioxane / 0.5 h / Ambient temperature

With hydrogenchloride; potassium hydroxide; hydrogen; triethylamine; diethyl dicarbonate; rhodium on alumina; In tetrahydrofuran; 1,4-dioxane; ethanol;
DOI:10.1248/cpb.38.103