N-(5-(3-benzyl-1-bromo-3H-pyrazolo[3,4-c]quinolin-8-yl)pyridin-3-yl)acetamide

Base Information

Chemical Name:N-(5-(3-benzyl-1-bromo-3H-pyrazolo[3,4-c]quinolin-8-yl)pyridin-3-yl)acetamide
CAS No.:1201646-58-3
Molecular Formula:C₂₄H₁₈BrN₅O
Molecular Weight:472.344
Hs Code.:

Synonyms:N-(5-(3-benzyl-1-bromo-3H-pyrazolo[3,4-c]quinolin-8-yl)pyridin-3-yl)acetamide

Suppliers and Price of N-(5-(3-benzyl-1-bromo-3H-pyrazolo[3,4-c]quinolin-8-yl)pyridin-3-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(5-(3-benzyl-1-bromo-3H-pyrazolo[3,4-c]quinolin-8-yl)pyridin-3-yl)acetamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(5-(3-benzyl-1-bromo-3H-pyrazolo[3,4-c]quinolin-8-yl)pyridin-3-yl)acetamide

There total 15 articles about N-(5-(3-benzyl-1-bromo-3H-pyrazolo[3,4-c]quinolin-8-yl)pyridin-3-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: N-(5-(1-bromo-3H-pyrazolo[3,4-c]quinolin-8-yl)pyridin-3-yl)acetamide

: 100-39-0
benzyl bromide

: 1201646-58-3
N-(5-(3-benzyl-1-bromo-3H-pyrazolo[3,4-c]quinolin-8-yl)pyridin-3-yl)acetamide

Guidance literature:: With potassium carbonate; In ethanol; for 2h; Reflux;

Reference yield:

: 1201643-75-5
(E)-5-bromo-2-((2-nitrovinyl)amino)benzoic acid

: 1201646-58-3
N-(5-(3-benzyl-1-bromo-3H-pyrazolo[3,4-c]quinolin-8-yl)pyridin-3-yl)acetamide

Guidance literature:: Multi-step reaction with 12 steps

1.1: potassium acetate / acetic anhydride / 1.5 h / 120 °C

2.1: N-ethyl-N,N-diisopropylamine; trichlorophosphate / acetonitrile / 2 h / 0 - 100 °C

3.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 80 °C

3.2: 20 °C

4.1: hydrogenchloride; water / Reflux

5.1: iron; acetic acid / 0.5 h / 20 °C

6.1: potassium acetate / toluene / 2 h / 60 °C

6.2: 8 h / 85 °C / Inert atmosphere

7.1: methanol; potassium carbonate / 2 h / Reflux

8.1: ethanol / 2 h / Reflux

9.1: potassium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl-formamide / 8 h / 155 °C / Inert atmosphere

10.1: potassium tert-butylate; oxygen; dimethyl sulfoxide / tetrahydrofuran / 0.17 h / 20 °C

11.1: N-Bromosuccinimide / acetonitrile / 0.5 h / Reflux

12.1: potassium carbonate / ethanol / 2 h / Reflux

With hydrogenchloride; methanol; N-Bromosuccinimide; potassium tert-butylate; water; oxygen; potassium acetate; iron; sodium hydride; potassium carbonate; acetic acid; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine; trichlorophosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; ethanol; acetic anhydride; N,N-dimethyl-formamide; toluene; acetonitrile;

Reference yield:

: 723281-72-9
6-bromo-4-chloro-3-nitroquinoline

: 1201646-58-3
N-(5-(3-benzyl-1-bromo-3H-pyrazolo[3,4-c]quinolin-8-yl)pyridin-3-yl)acetamide

Guidance literature:: Multi-step reaction with 10 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 80 °C

1.2: 20 °C

2.1: hydrogenchloride; water / Reflux

3.1: iron; acetic acid / 0.5 h / 20 °C

4.1: potassium acetate / toluene / 2 h / 60 °C

4.2: 8 h / 85 °C / Inert atmosphere

5.1: methanol; potassium carbonate / 2 h / Reflux

6.1: ethanol / 2 h / Reflux

7.1: potassium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl-formamide / 8 h / 155 °C / Inert atmosphere

8.1: potassium tert-butylate; oxygen; dimethyl sulfoxide / tetrahydrofuran / 0.17 h / 20 °C

9.1: N-Bromosuccinimide / acetonitrile / 0.5 h / Reflux

10.1: potassium carbonate / ethanol / 2 h / Reflux

With hydrogenchloride; methanol; N-Bromosuccinimide; potassium tert-butylate; water; oxygen; potassium acetate; iron; sodium hydride; potassium carbonate; acetic acid; dimethyl sulfoxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide; toluene; acetonitrile;