5-((2S,6R,7R,E)-6-(tert-butyldimethylsilyloxy)-2,7-dimethylnon-4-enylthio)-1-phenyl-1H-tetrazole

Base Information

Chemical Name:5-((2S,6R,7R,E)-6-(tert-butyldimethylsilyloxy)-2,7-dimethylnon-4-enylthio)-1-phenyl-1H-tetrazole
CAS No.:1443651-28-2
Molecular Formula:C₂₄H₄₀N₄OSSi
Molecular Weight:460.759
Hs Code.:

Synonyms:5-((2S,6R,7R,E)-6-(tert-butyldimethylsilyloxy)-2,7-dimethylnon-4-enylthio)-1-phenyl-1H-tetrazole

Suppliers and Price of 5-((2S,6R,7R,E)-6-(tert-butyldimethylsilyloxy)-2,7-dimethylnon-4-enylthio)-1-phenyl-1H-tetrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-((2S,6R,7R,E)-6-(tert-butyldimethylsilyloxy)-2,7-dimethylnon-4-enylthio)-1-phenyl-1H-tetrazole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-((2S,6R,7R,E)-6-(tert-butyldimethylsilyloxy)-2,7-dimethylnon-4-enylthio)-1-phenyl-1H-tetrazole

There total 7 articles about 5-((2S,6R,7R,E)-6-(tert-butyldimethylsilyloxy)-2,7-dimethylnon-4-enylthio)-1-phenyl-1H-tetrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 1443650-75-6
(2R,3R)-2-(tert-butyldimethylsilyloxy)-3-methylpentanal

: 1443650-82-5
(S)-5-(2-methyl-4-(1-phenyl-1H-tetrazol-5-ylsulfonyl)butylthio)-1-phenyl-1H-tetrazole

: 1443651-28-2
5-((2S,6R,7R,E)-6-(tert-butyldimethylsilyloxy)-2,7-dimethylnon-4-enylthio)-1-phenyl-1H-tetrazole

Guidance literature:: With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;
DOI:10.1002/chem.201204545

Reference yield:

: 1228675-56-6
(((2R,3R)-1-(benzyloxy)-3-methylpent-4-en-2-yl)oxy)(tert-butyl)dimethylsilane

: 1443651-28-2
5-((2S,6R,7R,E)-6-(tert-butyldimethylsilyloxy)-2,7-dimethylnon-4-enylthio)-1-phenyl-1H-tetrazole

Guidance literature:: Multi-step reaction with 3 steps

1: palladium hydroxide, 20 wt% on carbon; hydrogen / ethanol / 2 h / 20 °C / 759.83 Torr

2: Dess-Martin periodane / dichloromethane / 2 h / 20 °C / Inert atmosphere

3: sodium hexamethyldisilazane / tetrahydrofuran / -78 - 20 °C / Inert atmosphere

With palladium hydroxide, 20 wt% on carbon; hydrogen; sodium hexamethyldisilazane; Dess-Martin periodane; In tetrahydrofuran; ethanol; dichloromethane; 2: |Dess-Martin Oxidation / 3: |Julia-Kocienski Olefination;
DOI:10.1002/chem.201204545

Reference yield:

: 1443650-77-8
C₁₂H₂₈O₂Si

: 1443651-28-2
5-((2S,6R,7R,E)-6-(tert-butyldimethylsilyloxy)-2,7-dimethylnon-4-enylthio)-1-phenyl-1H-tetrazole

Guidance literature:: Multi-step reaction with 2 steps

1: Dess-Martin periodane / dichloromethane / 2 h / 20 °C / Inert atmosphere

2: sodium hexamethyldisilazane / tetrahydrofuran / -78 - 20 °C / Inert atmosphere

With sodium hexamethyldisilazane; Dess-Martin periodane; In tetrahydrofuran; dichloromethane; 1: |Dess-Martin Oxidation / 2: |Julia-Kocienski Olefination;
DOI:10.1002/chem.201204545