Benzenamine, 2-(difluoromethyl)-4-methoxy- (9CI)

Base Information

Chemical Name:Benzenamine, 2-(difluoromethyl)-4-methoxy- (9CI)
CAS No.:727993-36-4
Molecular Formula:C8H9 F2 N O
Molecular Weight:173.162
Hs Code.:
Mol file:727993-36-4.mol

Synonyms:2-(Difluoromethyl)-4-(methyloxy)aniline

Suppliers and Price of Benzenamine, 2-(difluoromethyl)-4-methoxy- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(DIFLUOROMETHYL)-4-METHOXYANILINE 95.00%
5MG
$ 498.83

A1 Biochem Labs
2-(Difluoromethyl)-4-methoxyaniline 95%
2.5 g
$ 1200.00

Total 2 raw suppliers

Chemical Property of Benzenamine, 2-(difluoromethyl)-4-methoxy- (9CI)

Chemical Property:

PSA：35.25000
LogP:2.79620

Purity/Quality:

99%+ ^*data from raw suppliers

2-(DIFLUOROMETHYL)-4-METHOXYANILINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 2-(Difluoromethyl)-4-(methyloxy)aniline are used in the preparation of CRF antagonists.

Technology Process of Benzenamine, 2-(difluoromethyl)-4-methoxy- (9CI)

There total 1 articles about Benzenamine, 2-(difluoromethyl)-4-methoxy- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

: 727993-35-3
2-(difluoromethyl)-4-(methyloxy)-2-nitrobenzene

: 727993-36-4
2-(difluoromethyl)-4-(methyloxy)aniline

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃; for 5h;

Reference yield:

: 727993-36-4
2-(difluoromethyl)-4-(methyloxy)aniline

: 491864-74-5
2-chloro-3-(2-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}ethyl)-6-methyl-4-[3-(1,3-thiazol-2-yl)-1H-pyrazol-1-yl]pyridine

: 727993-13-7
N-[2-(difluoromethyl)-4-(methyloxy)phenyl]-3-(2-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}ethyl)-6-methyl-4-[3-(1,3-thiazol-2-yl)-1H-pyrazol-1-yl]-2-pyridinamine

Guidance literature:: With potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2-(dicyclohexylphosphino)-2'-methylbiphenyl; In 1,2-dimethoxyethane; at 100 ℃; for 0.666667h; under 3102.97 Torr; Inert atmosphere; Microwave irradiation;
DOI:10.1021/jm800743q