bis(3,5-dimethylphenyl)phosphinic amide

Base Information

• Chemical Name: bis(3,5-dimethylphenyl)phosphinic amide
• CAS No.: 1201903-43-6
• Molecular Formula: C₁₆H₂₀NOP
• Molecular Weight: 273.315
• Mol file: 1201903-43-6.mol

Synonyms:bis(3,5-dimethylphenyl)phosphinic amide

Chemical Property of bis(3,5-dimethylphenyl)phosphinic amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis(3,5-dimethylphenyl)phosphinic amide

There total 3 articles about bis(3,5-dimethylphenyl)phosphinic amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

Bis(3,5-dimethylphenyl)phosphinic acid (137219-82-0) → bis(3,5-dimethylphenyl)phosphinic amide (1201903-43-6)

Guidance literature:

Bis(3,5-dimethylphenyl)phosphinic acid; With thionyl chloride; In toluene; at 55 - 60 ℃; for 0.333333h;

With ammonia; In toluene; at -20 ℃;

Reference yield:

(3-(chloro(3,5-dimethylphenyl)phosphoryl)-5-methylphenyl)methylium (137219-83-1) → bis(3,5-dimethylphenyl)phosphinic amide (1201903-43-6)

Guidance literature:

With ammonia; In toluene; at 0 ℃; for 0.166667h;

DOI:10.1021/cm201940f

Reference yield:

5-bromo-1,3-xylene (556-96-7) → bis(3,5-dimethylphenyl)phosphinic amide (1201903-43-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: magnesium / tetrahydrofuran / 20 °C

1.2: 20 °C

1.3: 1 h / 80 °C

2.1: thionyl chloride / toluene / 55 - 60 °C

3.1: ammonia / toluene / 0.17 h / 0 °C

With thionyl chloride; ammonia; magnesium; In tetrahydrofuran; toluene;

DOI:10.1021/cm201940f

upstream raw materials:

Bis(3,5-dimethylphenyl)phosphinic acid

5-bromo-1,3-xylene

(3-(chloro(3,5-dimethylphenyl)phosphoryl)-5-methylphenyl)methylium

Downstream raw materials:

2,2,4,4,6,6-hexa(3,5-dimethylphenyl)cyclotriphosphazene