Technology Process of ethyl 6-(4-aminophenyl)-4-methyl-2-pyridinecarboxylate hydrochloride
There total 6 articles about ethyl 6-(4-aminophenyl)-4-methyl-2-pyridinecarboxylate hydrochloride which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 30percent aq. H2O2 / acetic acid / 20 h / 80 °C
2: 1.) Me2SO4 / 1.) 80-90 deg C, 2 h, 2.) dioxane, H2O, RT, 30 min
3: 5 M aq. HCl / 11 h / Heating
4: H2, AcONa / 10percent Pd/C / dimethylformamide
5: SOCl2 / 4 h / Heating
With
hydrogenchloride; thionyl chloride; hydrogen; dihydrogen peroxide; sodium acetate; dimethyl sulfate;
palladium on activated charcoal;
In
acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm00364a026
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) Me2SO4 / 1.) 80-90 deg C, 2 h, 2.) dioxane, H2O, RT, 30 min
2: 5 M aq. HCl / 11 h / Heating
3: H2, AcONa / 10percent Pd/C / dimethylformamide
4: SOCl2 / 4 h / Heating
With
hydrogenchloride; thionyl chloride; hydrogen; sodium acetate; dimethyl sulfate;
palladium on activated charcoal;
In
N,N-dimethyl-formamide;
DOI:10.1021/jm00364a026
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 5 M aq. HCl / 11 h / Heating
2: H2, AcONa / 10percent Pd/C / dimethylformamide
3: SOCl2 / 4 h / Heating
With
hydrogenchloride; thionyl chloride; hydrogen; sodium acetate;
palladium on activated charcoal;
In
N,N-dimethyl-formamide;
DOI:10.1021/jm00364a026
