1-Ethynylcyclohexane-1,2-diol

Base Information

Chemical Name:1-Ethynylcyclohexane-1,2-diol
CAS No.:75476-42-5
Molecular Formula:C8H12 O2
Molecular Weight:140.17968
Hs Code.:
DSSTox Substance ID:DTXSID00505782
Mol file:75476-42-5.mol

Synonyms:1-Ethynylcyclohexane-1,2-diol;DTXSID00505782;75476-42-5

Suppliers and Price of 1-Ethynylcyclohexane-1,2-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-Ethynylcyclohexane-1,2-diol

Chemical Property:

PSA：40.46000
LogP:0.28560
XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:140.083729621
Heavy Atom Count:10
Complexity:167

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C#CC1(CCCCC1O)O

Technology Process of 1-Ethynylcyclohexane-1,2-diol

There total 6 articles about 1-Ethynylcyclohexane-1,2-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1428560-27-3
C₁₈H₂₀O₅

: 7312-60-9,75476-41-4,75476-42-5
trans-1-Aethinyl-cyclohexandiol-(1,2)

Guidance literature:: With lithium hydroxide monohydrate; In tetrahydrofuran; water; at 20 ℃; for 4h;
DOI:10.1021/ol400549q

Reference yield: 2.0%

: 932-03-6
1-Ethynyl-7-oxa-bicyclo[4.1.0]heptane

: 75476-42-5
1-ethenyl-r-1-c-2-cyclohexane-1,2-diol

: 75476-41-4
1-ethenyl-r-1-t-2-cyclohexane-1,2-diol

Guidance literature:: With sulfuric acid; In water;
DOI:10.1021/jo00315a039

Reference yield:

: 75476-42-5
1-ethenyl-r-1-c-2-cyclohexane-1,2-diol

: 7312-60-9,75476-41-4,75476-42-5
trans-1-Aethinyl-cyclohexandiol-(1,2)

Guidance literature:: Multi-step reaction with 2 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 12 h / 20 °C

2: lithium hydroxide monohydrate / water; tetrahydrofuran / 4 h / 20 °C

With dmap; lithium hydroxide monohydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; dichloromethane; water;
DOI:10.1021/ol400549q