(E)-4-(3-oxo-3-phenethoxyprop-1-enyl)-1,2-phenylene diacetate

Base Information

• Chemical Name: (E)-4-(3-oxo-3-phenethoxyprop-1-enyl)-1,2-phenylene diacetate
• CAS No.: 118971-54-3
• Molecular Formula: C₂₁H₂₀O₆
• Molecular Weight: 368.386
• Mol file: 118971-54-3.mol

Synonyms:(E)-4-(3-oxo-3-phenethoxyprop-1-enyl)-1,2-phenylene diacetate

Chemical Property of (E)-4-(3-oxo-3-phenethoxyprop-1-enyl)-1,2-phenylene diacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (E)-4-(3-oxo-3-phenethoxyprop-1-enyl)-1,2-phenylene diacetate

There total 2 articles about (E)-4-(3-oxo-3-phenethoxyprop-1-enyl)-1,2-phenylene diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

2-phenylethanol (60-12-8) + 3,4-diacetoxycinnamic acid (88623-81-8) → (E)-4-(3-oxo-3-phenethoxyprop-1-enyl)-1,2-phenylene diacetate (118971-54-3)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In toluene; at 90 ℃; for 3h; Inert atmosphere;

DOI:10.1016/j.ejmech.2014.01.049

Reference yield:

caffeic acid (331-39-5,501-16-6) → (E)-4-(3-oxo-3-phenethoxyprop-1-enyl)-1,2-phenylene diacetate (118971-54-3)

Guidance literature:

Multi-step reaction with 2 steps

1: dmap; pyridine / 2 h / 20 °C / Inert atmosphere

2: dicyclohexyl-carbodiimide; dmap / toluene / 3 h / 90 °C / Inert atmosphere

With pyridine; dmap; dicyclohexyl-carbodiimide; In toluene;

DOI:10.1016/j.ejmech.2014.01.049

Reference yield: 75.0%

(E)-4-(3-oxo-3-phenethoxyprop-1-enyl)-1,2-phenylene diacetate (118971-54-3) → Caffeic acid phenethyl ester (104594-70-9,115610-29-2,132336-00-6)

Guidance literature:

With pyrrolidine; In tetrahydrofuran; at 20 ℃; for 0.5h;

DOI:10.1016/j.ejmech.2014.01.049

upstream raw materials:

caffeic acid

2-phenylethanol

3,4-diacetoxycinnamic acid

Downstream raw materials:

Caffeic acid phenethyl ester

Refernces