2-[[[[4'-(trifluoromethoxy)[1,1'-biphenyl]-4-yl]sulfonyl](phenylmethoxycarbonyl)amino]methyl]-1-naphthalenecarboxylic Acid

Base Information

Chemical Name:2-[[[[4'-(trifluoromethoxy)[1,1'-biphenyl]-4-yl]sulfonyl](phenylmethoxycarbonyl)amino]methyl]-1-naphthalenecarboxylic Acid
CAS No.:279246-06-9
Molecular Formula:C₃₃H₂₄F₃NO₇S
Molecular Weight:635.617
Hs Code.:

Synonyms:2-[[[[4'-(trifluoromethoxy)[1,1'-biphenyl]-4-yl]sulfonyl](phenylmethoxycarbonyl)amino]methyl]-1-naphthalenecarboxylic Acid

Suppliers and Price of 2-[[[[4'-(trifluoromethoxy)[1,1'-biphenyl]-4-yl]sulfonyl](phenylmethoxycarbonyl)amino]methyl]-1-naphthalenecarboxylic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[[[[4'-(trifluoromethoxy)[1,1'-biphenyl]-4-yl]sulfonyl](phenylmethoxycarbonyl)amino]methyl]-1-naphthalenecarboxylic Acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[[[[4'-(trifluoromethoxy)[1,1'-biphenyl]-4-yl]sulfonyl](phenylmethoxycarbonyl)amino]methyl]-1-naphthalenecarboxylic Acid

There total 3 articles about 2-[[[[4'-(trifluoromethoxy)[1,1'-biphenyl]-4-yl]sulfonyl](phenylmethoxycarbonyl)amino]methyl]-1-naphthalenecarboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 279246-05-8
1,1-dimethylethyl 2-[[[[4'-(trifluoromethoxy)[1,1'-biphenyl]-4-yl]sulfonyl](phenylmethoxycarbonyl)amino]methyl]-1-naphthalenecarboxylate

: 279246-06-9
2-[[[[4'-(trifluoromethoxy)[1,1'-biphenyl]-4-yl]sulfonyl](phenylmethoxycarbonyl)amino]methyl]-1-naphthalenecarboxylic Acid

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 1h;
DOI:10.1021/jm020160g

Reference yield:

: 7647-01-0,15364-23-5
hydrogenchloride

: 279246-05-8
1,1-dimethylethyl 2-[[[[4'-(trifluoromethoxy)[1,1'-biphenyl]-4-yl]sulfonyl](phenylmethoxycarbonyl)amino]methyl]-1-naphthalenecarboxylate

: 279246-06-9
2-[[[[4'-(trifluoromethoxy)[1,1'-biphenyl]-4-yl]sulfonyl](phenylmethoxycarbonyl)amino]methyl]-1-naphthalenecarboxylic Acid

Guidance literature:: With trifluoroacetic acid; In dichloromethane;

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 279246-06-9
2-[[[[4'-(trifluoromethoxy)[1,1'-biphenyl]-4-yl]sulfonyl](phenylmethoxycarbonyl)amino]methyl]-1-naphthalenecarboxylic Acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaH / dimethylformamide / 0.5 h

1.2: 77 percent / dimethylformamide / 2 h

2.1: 100 percent / TFA / CH₂Cl₂ / 1 h / 0 °C

With sodium hydride; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm020160g