2,3-diethyl 4-methyl 1-(4-methoxybenzyl)-5-methyl-1H-pyrrole-2,3,4-tricarboxylate

Base Information

• Chemical Name: 2,3-diethyl 4-methyl 1-(4-methoxybenzyl)-5-methyl-1H-pyrrole-2,3,4-tricarboxylate
• CAS No.: 1620103-01-6
• Molecular Formula: C₂₁H₂₅NO₇
• Molecular Weight: 403.432
• Mol file: 1620103-01-6.mol

Synonyms:2,3-diethyl 4-methyl 1-(4-methoxybenzyl)-5-methyl-1H-pyrrole-2,3,4-tricarboxylate

Chemical Property of 2,3-diethyl 4-methyl 1-(4-methoxybenzyl)-5-methyl-1H-pyrrole-2,3,4-tricarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-diethyl 4-methyl 1-(4-methoxybenzyl)-5-methyl-1H-pyrrole-2,3,4-tricarboxylate

There total 3 articles about 2,3-diethyl 4-methyl 1-(4-methoxybenzyl)-5-methyl-1H-pyrrole-2,3,4-tricarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C13H18O7 (1620102-90-0) + 4-methoxy-benzylamine (2393-23-9) → 2,3-diethyl 4-methyl 1-(4-methoxybenzyl)-5-methyl-1H-pyrrole-2,3,4-tricarboxylate (1620103-01-6)

Guidance literature:

With acetic acid; In ethanol; for 12h; Reflux;

DOI:10.1016/j.tetlet.2014.06.025

Reference yield:

acetoacetic acid methyl ester (105-45-3) → 2,3-diethyl 4-methyl 1-(4-methoxybenzyl)-5-methyl-1H-pyrrole-2,3,4-tricarboxylate (1620103-01-6)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / ethanol / 3 h / 20 °C

2: acetic acid / ethanol / 12 h / Reflux

With potassium carbonate; acetic acid; In ethanol;

DOI:10.1016/j.tetlet.2014.06.025

Reference yield:

acetylenedicarboxylic acid diethyl ester (762-21-0) → 2,3-diethyl 4-methyl 1-(4-methoxybenzyl)-5-methyl-1H-pyrrole-2,3,4-tricarboxylate (1620103-01-6)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / ethanol / 3 h / 20 °C

2: acetic acid / ethanol / 12 h / Reflux

With potassium carbonate; acetic acid; In ethanol;

DOI:10.1016/j.tetlet.2014.06.025

upstream raw materials:

C₁₃H₁₈O₇

4-methoxy-benzylamine

acetoacetic acid methyl ester

acetylenedicarboxylic acid diethyl ester