3,6,9,12-tetraoxatetradecanoic acid 14-[[tetrahydro-2H-pyran-2-yl]oxy]phenylmethyl ester

Base Information

• Chemical Name: 3,6,9,12-tetraoxatetradecanoic acid 14-[[tetrahydro-2H-pyran-2-yl]oxy]phenylmethyl ester
• CAS No.: 1318760-40-5
• Molecular Formula: C₂₂H₃₄O₈
• Molecular Weight: 426.507
• Mol file: 1318760-40-5.mol

Synonyms:3,6,9,12-tetraoxatetradecanoic acid 14-[[tetrahydro-2H-pyran-2-yl]oxy]phenylmethyl ester

Chemical Property of 3,6,9,12-tetraoxatetradecanoic acid 14-[[tetrahydro-2H-pyran-2-yl]oxy]phenylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,6,9,12-tetraoxatetradecanoic acid 14-[[tetrahydro-2H-pyran-2-yl]oxy]phenylmethyl ester

There total 1 articles about 3,6,9,12-tetraoxatetradecanoic acid 14-[[tetrahydro-2H-pyran-2-yl]oxy]phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

benzyl bromide (100-39-0) + 2-(2-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethan-1-ol (128660-97-9) + bromoacetic acid (79-08-3) → 3,6,9,12-tetraoxatetradecanoic acid 14-[[tetrahydro-2H-pyran-2-yl]oxy]phenylmethyl ester (1318760-40-5)

Guidance literature:

2-(2-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethan-1-ol; With sodium hydride; In tetrahydrofuran; for 1h; Inert atmosphere;

bromoacetic acid; In tetrahydrofuran; for 16h; Reflux;

benzyl bromide; In tetrahydrofuran; for 16h; Reflux;

DOI:10.1016/j.bmc.2011.05.002

Reference yield: 83.0%

3,6,9,12-tetraoxatetradecanoic acid 14-[[tetrahydro-2H-pyran-2-yl]oxy]phenylmethyl ester (1318760-40-5) → 14-hydroxy-3,6,9,12-tetraoxatetradecanoic acid phenylmethyl ester (195071-47-7)

Guidance literature:

With pyridinium p-toluenesulfonate; In ethanol; at 44.84 ℃; for 16h;

DOI:10.1016/j.bmc.2011.05.002

upstream raw materials:

benzyl bromide

2-(2-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethan-1-ol

bromoacetic acid

Downstream raw materials:

14-hydroxy-3,6,9,12-tetraoxatetradecanoic acid phenylmethyl ester