THP-PEG5

Base Information

Chemical Name:THP-PEG5
CAS No.:128660-97-9
Molecular Formula:C13H26O6
Molecular Weight:278.346
Hs Code.:
Mol file:128660-97-9.mol

Synonyms:3,6,9,12-tetraoxa-12-(2-tetrahydropyranyl)dodecan-1-ol;11-(2H-tetrahydropyran-2'-yloxy)-3,6,9-trioxaundecan-1-ol;2-(2-(2-(2-(tetrahydro-2H-pyran-2-yloxy)ethoxy)ethoxy)ethoxy)ethanol;2-(2-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethanol;2-(2-{2-[2-(tetrahydropyran-2-yloxy)ethoxy]ethoxy}ethoxy)ethanol;2-{2-[2-(2-(tetrahydropyran-2-yloxy)ethoxy]ethoxy}ethoxy)ethanol;2-(2-{2-[2-(Tetrahydro-pyran-2-yloxy)-ethoxy]-ethoxy}-ethoxy)-ethanol;

Suppliers and Price of THP-PEG5

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
THP-PEG5
10mg
$ 45.00

Matrix Scientific
2-(2-{2-[2-(Tetrahydropyran-2-yloxy)-ethoxy]-ethoxy}-ethoxy)-ethanol 95%
10g
$ 1733.00

Matrix Scientific
2-(2-{2-[2-(Tetrahydropyran-2-yloxy)-ethoxy]-ethoxy}-ethoxy)-ethanol 95%
5g
$ 990.00

Matrix Scientific
2-(2-{2-[2-(Tetrahydropyran-2-yloxy)-ethoxy]-ethoxy}-ethoxy)-ethanol 95%
1g
$ 413.00

BroadPharm
THP-PEG5 98%
1 G
$ 280.00

Apolloscientific
THP-PEG5
1g
$ 546.00

Acrotein
THP-PEG4-OH 97%
1g
$ 247.50

Acrotein
THP-PEG4-OH 97%
0.5g
$ 165.00

Acrotein
THP-PEG4-OH 97%
5g
$ 742.50

A1 Biochem Labs
2-(2-{2-[2-(Tetrahydro-pyran-2-yloxy)-ethoxy]-ethoxy}-ethoxy)-ethanol 95%
5 g
$ 600.00

Total 9 raw suppliers

Chemical Property of THP-PEG5

Chemical Property:

PSA：66.38000
LogP:0.57170

Purity/Quality:

99.3% ^*data from raw suppliers

THP-PEG5 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description THP-PEG5 is a PEG linker containing a THP protecting group and a terminal hydroxyl group. THP is an acid labile, alcohol protecting group. The terminal hydroxyl group can undergo reactions to further derivatize the compound. The hydrophilic PEG linkers increase the water solubility properties of the compound in aqueous media.

Technology Process of THP-PEG5

There total 3 articles about THP-PEG5 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 110-87-2
3,4-dihydro-2H-pyran

: 112-60-7
Tetraethylene glycol

: 128660-97-9
2-(2-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethan-1-ol

Guidance literature:: With p-toluenesulfonic acid monohydrate; In dichloromethane; at 20 ℃; Cooling with ice; Inert atmosphere;
DOI:10.1039/b718888a

Reference yield: 16.0%

: 128660-97-9
2-(2-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethan-1-ol

Guidance literature:: With toluene-4-sulfonic acid; In dichloromethane; at 0 ℃; for 4h;

Reference yield:

: 110-87-2
3,4-dihydro-2H-pyran

: 112-60-7
Tetraethylene glycol

: O(CH₂CH₂O)4(CH(CH₂)4O)2

: 128660-97-9
2-(2-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethan-1-ol

Guidance literature:: With toluene-4-sulfonic acid; In tetrahydrofuran; at 20 ℃; for 2h; Title compound not separated from byproducts.;
DOI:10.1021/ma051479o