4-[2-(N-benzyl-N-(2-hydroxy-3-phenoxypropyl)amino)ethyl]phenol

Base Information

• Chemical Name: 4-[2-(N-benzyl-N-(2-hydroxy-3-phenoxypropyl)amino)ethyl]phenol
• CAS No.: 125793-86-4
• Molecular Formula: C₂₄H₂₇NO₃
• Molecular Weight: 377.483
• Mol file: 125793-86-4.mol

Synonyms:4-[2-(N-benzyl-N-(2-hydroxy-3-phenoxypropyl)amino)ethyl]phenol

Chemical Property of 4-[2-(N-benzyl-N-(2-hydroxy-3-phenoxypropyl)amino)ethyl]phenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-[2-(N-benzyl-N-(2-hydroxy-3-phenoxypropyl)amino)ethyl]phenol

There total 4 articles about 4-[2-(N-benzyl-N-(2-hydroxy-3-phenoxypropyl)amino)ethyl]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenyl-2,3-epoxypropyl ether + 4-(2-benzylamino-ethyl)-phenol; hydrochloride (60000-00-2) → 4-[2-(N-benzyl-N-(2-hydroxy-3-phenoxypropyl)amino)ethyl]phenol (125793-86-4)

Guidance literature:

With triethylamine; In methanol; dichloromethane; isopropyl alcohol; toluene;

Reference yield:

tyrosamine (51-67-2) → 4-[2-(N-benzyl-N-(2-hydroxy-3-phenoxypropyl)amino)ethyl]phenol (125793-86-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 2.) NaBH₄ / 1.) EtOH, RT, 1.5 h, 2.) EtOH, RT, 3 h

2: propan-2-ol / 72 h / Heating

With sodium tetrahydroborate; In isopropyl alcohol;

DOI:10.1021/jm00088a010

Reference yield:

benzaldehyde (100-52-7) → 4-[2-(N-benzyl-N-(2-hydroxy-3-phenoxypropyl)amino)ethyl]phenol (125793-86-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 2.) NaBH₄ / 1.) EtOH, RT, 1.5 h, 2.) EtOH, RT, 3 h

2: propan-2-ol / 72 h / Heating

With sodium tetrahydroborate; In isopropyl alcohol;

DOI:10.1021/jm00088a010

upstream raw materials:

Phenyl glycidyl ether

N-benzyltyramine

tyrosamine

benzaldehyde

Downstream raw materials:

N-(4-[2-(N-benzyl-N-(2-hydroxy-3-phenoxypropyl)amino)ethyl]phenoxyacetyl)isooxazolidine

methyl 4-[2-(2-hydroxy-3-phenoxypropylamino)ethyl]phenoxyacetate

methyl 4-[2-(N-benzyl-N-(2-hydroxy-3-phenoxypropyl)amino)ethyl]phenoxyacetate