6-benzoyl-2-(pent-4-ynyl)-5-phenyl-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one

Base Information

Chemical Name:6-benzoyl-2-(pent-4-ynyl)-5-phenyl-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one
CAS No.:1616967-52-2
Molecular Formula:C₂₄H₁₉N₃O₂
Molecular Weight:381.434
Hs Code.:

Synonyms:6-benzoyl-2-(pent-4-ynyl)-5-phenyl-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one

Suppliers and Price of 6-benzoyl-2-(pent-4-ynyl)-5-phenyl-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-benzoyl-2-(pent-4-ynyl)-5-phenyl-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 6-benzoyl-2-(pent-4-ynyl)-5-phenyl-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one

There total 2 articles about 6-benzoyl-2-(pent-4-ynyl)-5-phenyl-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 77758-51-1
methyl hex-5-ynoate

: 1414841-38-5
2-amino-5-benzoyl-4-phenyl-1H-pyrrole-3-carboxamide

: 1616967-52-2
6-benzoyl-2-(pent-4-ynyl)-5-phenyl-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one

Guidance literature:: With sodium; In ethanol; for 10h; Reflux;
DOI:10.1002/cmdc.201300532

Reference yield:

: 100-52-7
benzaldehyde

: 1616967-52-2
6-benzoyl-2-(pent-4-ynyl)-5-phenyl-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / ethanol / 14 h / Reflux

2: sodium / ethanol / 10 h / Reflux

With sodium; potassium carbonate; In ethanol;
DOI:10.1002/cmdc.201300532

Reference yield: 78.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 1616967-52-2
6-benzoyl-2-(pent-4-ynyl)-5-phenyl-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one

: tert-butyl 6-benzoyl-4-oxo-2-(pent-4-yn-1-yl)-5-phenyl-1,4-dihydro-7H-pyrrolo[2,3-d]pyrimidine-7-carboxylate

Guidance literature:: 6-benzoyl-2-(pent-4-ynyl)-5-phenyl-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.25h;

di-tert-butyl dicarbonate; With dmap; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 4h;
DOI:10.1002/cmdc.201800658