2,5-Diazabicyclo[2.2.2]octane-3,6-dione,1,2,4-trimethyl-(9CI)

Base Information

Chemical Name:2,5-Diazabicyclo[2.2.2]octane-3,6-dione,1,2,4-trimethyl-(9CI)
CAS No.:723335-17-9
Molecular Formula:C₉H₁₄N₂O₂
Molecular Weight:182.222
Hs Code.:
Mol file:723335-17-9.mol

Synonyms:2,5-Diazabicyclo[2.2.2]octane-3,6-dione,1,2,4-trimethyl-(9CI);1,2,4-TRIMETHYL-2,5-DIAZABICYCLO[2.2.2]OCTANE-3,6-DIONE

Suppliers and Price of 2,5-Diazabicyclo[2.2.2]octane-3,6-dione,1,2,4-trimethyl-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 2,5-Diazabicyclo[2.2.2]octane-3,6-dione,1,2,4-trimethyl-(9CI)

Chemical Property:

PSA：52.90000
LogP:0.09960

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,5-Diazabicyclo[2.2.2]octane-3,6-dione,1,2,4-trimethyl-(9CI)

There total 4 articles about 2,5-Diazabicyclo[2.2.2]octane-3,6-dione,1,2,4-trimethyl-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 74-88-4
methyl iodide

: 723335-09-9
2-(4-methoxy-benzyl)-1,4-dimethyl-2,5-diaza-bicyclo[2.2.2]octane-3,6-dione

: 723335-17-9,817575-51-2
1,2,4-trimethyl-2,5-diaza-bicyclo[2.2.2]octane-3,6-dione

Guidance literature:: methyl iodide; 2-(4-methoxy-benzyl)-1,4-dimethyl-2,5-diaza-bicyclo[2.2.2]octane-3,6-dione; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃;

With ammonium cerium(IV) nitrate; In water; acetonitrile; at 0 ℃; Further stages.;
DOI:10.1016/j.tetlet.2004.03.186

Reference yield:

: 595581-86-5
5-chloro-1-(4-methoxybenzyl)-3,6-dimethyl-2(1H)-pyrazinone

: 723335-17-9,817575-51-2
1,2,4-trimethyl-2,5-diaza-bicyclo[2.2.2]octane-3,6-dione

Guidance literature:: Multi-step reaction with 3 steps

1.1: 89 percent / tetrahydrofuran / 135 °C / 25081.7 Torr

2.1: 64 percent / air moisture / CHCl₃ / 20 °C

3.1: NaH / dimethylformamide / 20 °C

3.2: cerium ammonium nitrate / H₂O; acetonitrile / 0 °C

With air moisture; sodium hydride; In tetrahydrofuran; chloroform; N,N-dimethyl-formamide;
DOI:10.1016/j.tetlet.2004.03.186

Reference yield:

: 595581-85-4
1-(4-methoxybenzyl)-3,5-dichloro-6-methyl-pyrazine-2(1H)-one

: 723335-17-9,817575-51-2
1,2,4-trimethyl-2,5-diaza-bicyclo[2.2.2]octane-3,6-dione

Guidance literature:: Multi-step reaction with 4 steps

1.1: 57 percent / tetrahydrofuran / -78 °C

2.1: 89 percent / tetrahydrofuran / 135 °C / 25081.7 Torr

3.1: 64 percent / air moisture / CHCl₃ / 20 °C

4.1: NaH / dimethylformamide / 20 °C

4.2: cerium ammonium nitrate / H₂O; acetonitrile / 0 °C

With air moisture; sodium hydride; In tetrahydrofuran; chloroform; N,N-dimethyl-formamide;
DOI:10.1016/j.tetlet.2004.03.186