595581-85-4

Upstream product

• 79-37-8 oxalyl dichloride 
• 777801-61-3 2-[(4-methoxybenzyl)amino]propionitrile 
• 1379244-21-9 C₁₂H₁₅NO 
• 2393-23-9 4-methoxy-benzylamine 

Downstream Products

• 595581-86-5 5-chloro-1-(4-methoxybenzyl)-3,6-dimethyl-2(1H)-pyrazinone 
• 817575-39-6 5-chloro-3-isopropyl-1-(4-methoxybenzyl)-6-methyl-2(1H)-pyrazinone 
• 1011736-34-7 1-(4-methoxybenzyl)-5-chloro-3-(2-cyclohexylethynyl)-6-methylpyrazin-2(1H)-one 
• 1011736-32-5 C₂₁H₁₇ClN₂O₂ 
• 1011736-33-6 C₁₉H₂₁ClN₂O₂ 
• 1178980-08-9 1-(4-methoxybenzyl)-5-chloro-3-(2-cyclopropylethynyl)-6-methylpyrazin-2(1H)-one 
• 1178980-04-5 1-(4-methoxybenzyl)-5-chloro-6-methyl-3-(2-o-tolylethynyl)pyrazin-2(1H)-one 
• 1205677-39-9 1-(4-methoxybenzyl)-5-chloro-3-methoxy-6-methylpyrazin-2(1H)-one 
• 1184851-91-9 5-chloro-1-(4-methoxybenzyl)-6-methyl-3-p-tolylpyrazin-2(1H)-one 
• 1277090-42-2 5-chloro-3-(4-methoxybenzoyl)-1-(4-methoxybenzyl)-6-methylpyrazin-2(1H)-one 
• 1369514-41-9 2-chloro-3-methyl-6-phenyl-7-vinyl-furo[2,3-b]pyrazine 
• 1369514-45-3 2-chloro-3-methyl-6-phenylfuro[3,2-b]pyrazine-7-carbaldehyde 
• 1369514-49-7 2-chloro-3-methyl-6-phenylfuro[3,2-b]pyrazine-7-carboxylic acid 
• 1369514-52-2 methyl 2-chloro-3-methyl-6-phenylfuro[3,2-b]pyrazine-7-carboxylate 

Relevant academic research and scientific papers

A straightforward microwave method for rapid synthesis of N-1, C-6 functionalized 3,5-dichloro-2(1H)-pyrazinones

A rapid and versatile one-pot, 2 × 10 min microwave protocol for the preparation of N-1 and C-6 decorated 3,5-dichloro-2(1H)-pyrazinones was developed. Comparable reaction sequences using classical conditions require about 1-2 days of heating. The α-amino

Diversity-oriented synthesis of substituted furo[2,3-b]pyrazines

A highly efficient method for the synthesis of diversely substituted furo[2,3-b]pyrazines has been elaborated. The Ag+- or iodine-mediated electrophilic cyclization of readily generated 5-chloro-3-substituted ethynyl-1-(4-methoxybenzyl)-pyrazin-2(1H)-ones affords substituted furo[2,3-b]pyrazines, which undergo various palladium catalyzed reactions to generate a library of difficult to attain diversely substituted furo[2,3-b]pyrazines. CSIRO 2009.

Synthesis and fungicidal activity of 3,5-dichloropyrazin-2(1H)-one derivatives

We synthesized a family of 3,5-dichloropyrazin-2(1H)-one derivatives and assessed their in vitro fungicidal activity against Candida albicans. Compounds 11 and 20 were most active against C. albicans and induced accumulation of reactive oxygen species in

Design and synthesis of novel type VI-like β-turn mimetics. Diversity at the i+1 and the i+2 position

In this paper, a synthetic approach for functionalised 5-aminopiperidinone- 2-carboxylate (APC) systems as non-pro cis-peptide bond containing external β-turn mimics is presented. The scope and limitations of the synthetic method are discussed and the pot

Development of a functionalizable external β-turn mimic based on a cis-fused 1,7-naphthyridine scaffold

An intramolecular Diels-Alder strategy using 2(1H)-pyrazinones was applied to generate a substituted perhydro-1,7-naphthyridine ring system that served as a scaffold to construct the type VI β-turn mimic 2, featuring a cis-amide linkage between the centra