4-fluorophenyl S-methylthiourea hydroiodide salt

Base Information

• Chemical Name: 4-fluorophenyl S-methylthiourea hydroiodide salt
• CAS No.: 21722-13-4
• Molecular Formula: C₈H₉FN₂S*HI
• Molecular Weight: 312.15
• Mol file: 21722-13-4.mol

Synonyms:4-fluorophenyl S-methylthiourea hydroiodide salt

Chemical Property of 4-fluorophenyl S-methylthiourea hydroiodide salt

Chemical Property:

Purity/Quality:

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Technology Process of 4-fluorophenyl S-methylthiourea hydroiodide salt

There total 4 articles about 4-fluorophenyl S-methylthiourea hydroiodide salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

(4-fluoro-phenyl)-thiourea (459-05-2) + methyl iodide (74-88-4) → 1-(4-Fluoro-phenyl)-2-methyl-isothiourea; hydriodide (21722-13-4)

Guidance literature:

In methanol; at 20 ℃;

DOI:10.1246/bcsj.73.2539

Reference yield: 70.0%

(4-fluoro-phenyl)-thiourea (459-05-2) + methyl iodide (74-88-4) → 1-(4-Fluoro-phenyl)-2-methyl-isothiourea; hydriodide (21722-13-4)

Guidance literature:

In methanol; for 2h; Ambient temperature;

DOI:10.1055/s-1988-27606

Reference yield:

(4-fluoro-phenyl)-thiourea (459-05-2) + methyl iodide (74-88-4) → 4-fluorophenyl S-methylthiourea hydroiodide salt (21722-13-4)

Guidance literature:

upstream raw materials:

(4-fluoro-phenyl)-thiourea

methyl iodide

Downstream raw materials:

N-(4-Fluoro-phenyl)-morpholine-4-carboxamidine; hydriodide

Refernces

• 1、 -. "PROKINETICIN 1 RECEPTOR". Page/Page column 68. . Retrieved 2008/06/13.
• 2、 Rasmussen, C. R.,Villani, F. J.,Reynolds, B. E.,Plampin, J. N.,Hood, A. R.,et al.. "A Versatile Synthesis of Novel N,N,N''-Trisubstituted Guanidines". . p. 460 - 466. Retrieved 2007/10/02.