(4R)-3-[(E)-3-(4-chlorophenyl)propenoyl]-2,2-dimethyl-4-phenyloxazolidine

Base Information

Chemical Name:(4R)-3-[(E)-3-(4-chlorophenyl)propenoyl]-2,2-dimethyl-4-phenyloxazolidine
CAS No.:1050593-77-5
Molecular Formula:C₂₀H₂₀ClNO₂
Molecular Weight:341.837
Hs Code.:

Synonyms:(4R)-3-[(E)-3-(4-chlorophenyl)propenoyl]-2,2-dimethyl-4-phenyloxazolidine

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Chemical Property of (4R)-3-[(E)-3-(4-chlorophenyl)propenoyl]-2,2-dimethyl-4-phenyloxazolidine

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Technology Process of (4R)-3-[(E)-3-(4-chlorophenyl)propenoyl]-2,2-dimethyl-4-phenyloxazolidine

There total 1 articles about (4R)-3-[(E)-3-(4-chlorophenyl)propenoyl]-2,2-dimethyl-4-phenyloxazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1050594-03-0
(4R)-3-(diethylphosphonoacetyl)-2,2-dimethyl-4-phenyloxazolidine

: 104-88-1
4-chlorobenzaldehyde

: 1050593-77-5
(4R)-3-[(E)-3-(4-chlorophenyl)propenoyl]-2,2-dimethyl-4-phenyloxazolidine

Guidance literature:: (4R)-3-(diethylphosphonoacetyl)-2,2-dimethyl-4-phenyloxazolidine; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 0.5h;

4-chlorobenzaldehyde; In tetrahydrofuran; at 20 ℃; for 16h; Further stages.;
DOI:10.1016/j.tet.2008.06.022

Reference yield: 84.0%

: 1050593-77-5
(4R)-3-[(E)-3-(4-chlorophenyl)propenoyl]-2,2-dimethyl-4-phenyloxazolidine

: 98-86-2
acetophenone

: 1050593-93-5
(4R)-3-[(2R,3R)-2-(4-chlorophenyl)-3-hydroxy-3-phenylbutanoyl]-2,2-dimethyl-4-phenyloxazolidine

Guidance literature:: With diethylzinc; cobalt acetylacetonate; In tetrahydrofuran; hexane; at 0 - 20 ℃; for 6h;
DOI:10.1016/j.tet.2008.06.022