Technology Process of (E)-N-methoxy-2-styrylbenzamide
There total 8 articles about (E)-N-methoxy-2-styrylbenzamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(E)-2-styrylbenzoic acid;
With
oxalyl dichloride; N,N-dimethyl-formamide;
In
dichloromethane;
at 0 - 20 ℃;
for 4h;
Under an atmosphere of argon;
N-methoxylamine hydrochloride;
With
potassium carbonate;
In
water; ethyl acetate;
at 0 - 20 ℃;
for 4h;
DOI:10.1021/ja109676d
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium pivalate; Trimethylacetic acid / methanol / 12 h / 80 °C / Under argon
2.1: potassium hydroxide / ethanol; water / 8 h / Reflux
3.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 4 h / 0 - 20 °C / Under an atmosphere of argon
3.2: 4 h / 0 - 20 °C
With
oxalyl dichloride; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; N,N-dimethyl-formamide; cesium pivalate; potassium hydroxide; Trimethylacetic acid;
In
methanol; ethanol; dichloromethane; water;
DOI:10.1021/ja109676d
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium pivalate; Trimethylacetic acid / methanol / 12 h / 80 °C / Under argon
2.1: potassium hydroxide / ethanol; water / 8 h / Reflux
3.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 4 h / 0 - 20 °C / Under an atmosphere of argon
3.2: 4 h / 0 - 20 °C
With
oxalyl dichloride; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; N,N-dimethyl-formamide; cesium pivalate; potassium hydroxide; Trimethylacetic acid;
In
methanol; ethanol; dichloromethane; water;
DOI:10.1021/ja109676d
