N-(3-{Acetyl-[4-(acetyl-phenyl-amino)-phenyl]-amino}-phenyl)-N-[4-(acetyl-phenyl-amino)-phenyl]-acetamide

Base Information

• Chemical Name: N-(3-{Acetyl-[4-(acetyl-phenyl-amino)-phenyl]-amino}-phenyl)-N-[4-(acetyl-phenyl-amino)-phenyl]-acetamide
• CAS No.: 184154-65-2
• Molecular Formula: C₃₈H₃₄N₄O₄
• Molecular Weight: 610.712
• Mol file: 184154-65-2.mol

Synonyms:N-(3-{Acetyl-[4-(acetyl-phenyl-amino)-phenyl]-amino}-phenyl)-N-[4-(acetyl-phenyl-amino)-phenyl]-acetamide

Chemical Property of N-(3-{Acetyl-[4-(acetyl-phenyl-amino)-phenyl]-amino}-phenyl)-N-[4-(acetyl-phenyl-amino)-phenyl]-acetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(3-{Acetyl-[4-(acetyl-phenyl-amino)-phenyl]-amino}-phenyl)-N-[4-(acetyl-phenyl-amino)-phenyl]-acetamide

There total 2 articles about N-(3-{Acetyl-[4-(acetyl-phenyl-amino)-phenyl]-amino}-phenyl)-N-[4-(acetyl-phenyl-amino)-phenyl]-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

1,3-dibromobenzene (108-36-1) + N,N'-diacetyl-N-phenyl-p-phenylenediamine (184154-64-1) → N-(3-{Acetyl-[4-(acetyl-phenyl-amino)-phenyl]-amino}-phenyl)-N-[4-(acetyl-phenyl-amino)-phenyl]-acetamide (184154-65-2)

Guidance literature:

With copper(l) iodide; potassium carbonate; In various solvent(s); for 24h; Heating;

DOI:10.1021/ja9616591

Reference yield:

N-phenylphenylene-1,4-diamine (101-54-2) → N-(3-{Acetyl-[4-(acetyl-phenyl-amino)-phenyl]-amino}-phenyl)-N-[4-(acetyl-phenyl-amino)-phenyl]-acetamide (184154-65-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / AcOH / 2 h / 70 °C

2: 51 percent / K₂CO₃, CuI / various solvent(s) / 24 h / Heating

With copper(l) iodide; potassium carbonate; acetic acid; In various solvent(s);

DOI:10.1021/ja9616591

Reference yield: 83.0%

N-(3-{Acetyl-[4-(acetyl-phenyl-amino)-phenyl]-amino}-phenyl)-N-[4-(acetyl-phenyl-amino)-phenyl]-acetamide (184154-65-2) → N,N'-bis[4-(N-phenylamino)phenyl]-1,3-benzenediamine (184154-66-3)

Guidance literature:

With sodium hydroxide; In ethanol; water; for 48h; Heating;

DOI:10.1021/ja9616591

upstream raw materials:

1,3-dibromobenzene

N,N'-diacetyl-N-phenyl-p-phenylenediamine

N-phenylphenylene-1,4-diamine

Downstream raw materials:

N,N'-bis[4-(N-phenylamino)phenyl]-1,3-benzenediamine