[3-[[(1,1-DIMETHYLETHYL)OXY]CARBONYL]-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPIN-7-YL]BORONIC ACID

Base Information

Chemical Name:[3-[[(1,1-DIMETHYLETHYL)OXY]CARBONYL]-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPIN-7-YL]BORONIC ACID
CAS No.:720692-77-3
Molecular Formula:C15H22 B N O4
Molecular Weight:291.155
Hs Code.:
Mol file:720692-77-3.mol

Synonyms:[3-[[(1,1-Dimethylethyl)oxy]carbonyl]-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl]boronicacid

Suppliers and Price of [3-[[(1,1-DIMETHYLETHYL)OXY]CARBONYL]-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPIN-7-YL]BORONIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-(TERT-BUTOXYCARBONYL)-2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPIN-7-YL-7-BORONIC ACID 95.00%
5MG
$ 503.49

Total 2 raw suppliers

Chemical Property of [3-[[(1,1-DIMETHYLETHYL)OXY]CARBONYL]-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPIN-7-YL]BORONIC ACID

Chemical Property:

PSA：70.00000
LogP:0.64000

Purity/Quality:

99% ^*data from raw suppliers

3-(TERT-BUTOXYCARBONYL)-2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPIN-7-YL-7-BORONIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of [3-[[(1,1-DIMETHYLETHYL)OXY]CARBONYL]-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPIN-7-YL]BORONIC ACID

There total 2 articles about [3-[[(1,1-DIMETHYLETHYL)OXY]CARBONYL]-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPIN-7-YL]BORONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 720692-76-2
t-butyl 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,4,5-tetrahydro-3-benzazepine-3-carboxylate

: 720692-77-3
(3-{[(1,1-dimethylethyl)oxy]carbonyl}-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)boronic acid

Guidance literature:: With sodium periodate; ammonium acetate; In water; at 20 ℃; for 18h;

Reference yield:

: 264264-28-0
1,1-dimethylethyl-7-{[(trifluoromethyl)sulfonyl]oxy}-1,2,4,5-tetrahydro-3H-3-benzazepine-3-carboxylate

: 720692-77-3
(3-{[(1,1-dimethylethyl)oxy]carbonyl}-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)boronic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium acetate / 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 3 h / 80 °C

2: sodium periodate; ammonium acetate / water / 18 h / 20 °C

With sodium periodate; ammonium acetate; potassium acetate; 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; water;

Reference yield:

: 720692-77-3
(3-{[(1,1-dimethylethyl)oxy]carbonyl}-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)boronic acid

: 589-15-1
1-bromomethyl-4-bromobenzene

: 1,1-dimethylethyl 7-[(4-bromophenyl)methyl]-1,2,4,5-tetrahydro-3H-3-benzazepine-3-carboxylate

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; water; toluene; at 20 ℃; for 5h; Heating / reflux;