Technology Process of C18H17NO4
There total 5 articles about C18H17NO4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium hexamethyldisilazane;
In
tetrahydrofuran; toluene;
at -78 ℃;
for 3h;
DOI:10.1002/anie.200701947
- Guidance literature:
-
Multi-step reaction with 4 steps
1: NaOH / methanol; H2O / 0.5 h / 0 °C
2: NaOAc / acetic anhydride / 0.5 h / 140 °C
3: 75 percent / Fe / acetic acid; toluene / 0.5 h / 110 °C
4: 96 percent / potassium hexamethyldisilazane / toluene; tetrahydrofuran / 3 h / -78 °C
With
potassium hexamethyldisilazane; sodium acetate; iron;
sodium hydroxide;
In
tetrahydrofuran; methanol; water; acetic anhydride; acetic acid; toluene;
1: Henry reaction;
DOI:10.1002/anie.200701947
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 96 percent / K2CO3 / dimethylformamide / 14 h / 0 - 23 °C
2: NaOH / methanol; H2O / 0.5 h / 0 °C
3: NaOAc / acetic anhydride / 0.5 h / 140 °C
4: 75 percent / Fe / acetic acid; toluene / 0.5 h / 110 °C
5: 96 percent / potassium hexamethyldisilazane / toluene; tetrahydrofuran / 3 h / -78 °C
With
potassium hexamethyldisilazane; sodium acetate; iron; potassium carbonate;
sodium hydroxide;
In
tetrahydrofuran; methanol; water; acetic anhydride; acetic acid; N,N-dimethyl-formamide; toluene;
2: Henry reaction;
DOI:10.1002/anie.200701947
