phenylmethyl 1-[(3-{4-[({[(1,1-dimethylethyl)oxy]carbonyl}amino)sulfonyl]-1-piperazinyl}phenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylate

Base Information

Chemical Name:phenylmethyl 1-[(3-{4-[({[(1,1-dimethylethyl)oxy]carbonyl}amino)sulfonyl]-1-piperazinyl}phenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylate
CAS No.:1018720-08-5
Molecular Formula:C₄₂H₄₈N₄O₆S
Molecular Weight:736.932
Hs Code.:

phenylmethyl 1-[(3-{4-[({[(1,1-dimethylethyl)oxy]carbonyl}amino)sulfonyl]-1-piperazinyl}phenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylate

Synonyms:phenylmethyl 1-[(3-{4-[({[(1,1-dimethylethyl)oxy]carbonyl}amino)sulfonyl]-1-piperazinyl}phenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylate

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Chemical Property of phenylmethyl 1-[(3-{4-[({[(1,1-dimethylethyl)oxy]carbonyl}amino)sulfonyl]-1-piperazinyl}phenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylate

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Technology Process of phenylmethyl 1-[(3-{4-[({[(1,1-dimethylethyl)oxy]carbonyl}amino)sulfonyl]-1-piperazinyl}phenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylate

There total 1 articles about phenylmethyl 1-[(3-{4-[({[(1,1-dimethylethyl)oxy]carbonyl}amino)sulfonyl]-1-piperazinyl}phenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1189-71-5
isocyanate de chlorosulfonyle

: 1010413-10-1
phenylmethyl 3-[4-(1,1-dimethylethyl)phenyl]-1-{[3-(1-piperazinyl)phenyl]methyl}-1H-indole-2-carboxylate

: 75-65-0
tert-butyl alcohol

: 1018720-08-5
phenylmethyl 1-[(3-{4-[({[(1,1-dimethylethyl)oxy]carbonyl}amino)sulfonyl]-1-piperazinyl}phenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylate

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 1h;

Reference yield:

: 1018720-08-5
phenylmethyl 1-[(3-{4-[({[(1,1-dimethylethyl)oxy]carbonyl}amino)sulfonyl]-1-piperazinyl}phenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylate

: 1-[(3-{4-[({[(1,1-dimethylethyl)oxy]carbonyl}amino)sulfonyl]-1-piperazinyl}phenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylic acid

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; chloroform; for 12h; under 760.051 Torr;

Reference yield:

: 1018720-08-5
phenylmethyl 1-[(3-{4-[({[(1,1-dimethylethyl)oxy]carbonyl}amino)sulfonyl]-1-piperazinyl}phenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylate

: 1018720-10-9
C₃₇H₄₀N₄O₄S

Guidance literature:: phenylmethyl 1-[(3-{4-[({[(1,1-dimethylethyl)oxy]carbonyl}amino)sulfonyl]-1-piperazinyl}phenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylate; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 4h;

With water; sodium carbonate; In ethyl acetate;