Technology Process of 7a-phenyl-3,3a,7,7a-tetrahydro-3,6-methanobenzofuran-2(6H)-one
There total 3 articles about 7a-phenyl-3,3a,7,7a-tetrahydro-3,6-methanobenzofuran-2(6H)-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1,3-bis-(1,3,5-trimethylphenyl)imidazol-2-ylidene;
In
1,2-dichloro-benzene;
at 0 ℃;
for 6h;
Reagent/catalyst;
Solvent;
Temperature;
Time;
Catalytic behavior;
Inert atmosphere;
Reflux;
DOI:10.1002/anie.201402067
- Guidance literature:
-
Multi-step reaction with 2 steps
1: dmap / acetonitrile / 1 h / 20 °C / Inert atmosphere
2: 1,3-bis-(1,3,5-trimethylphenyl)imidazol-2-ylidene / 1,2-dichloro-benzene / 6 h / 0 °C / Inert atmosphere; Reflux
With
dmap; 1,3-bis-(1,3,5-trimethylphenyl)imidazol-2-ylidene;
In
1,2-dichloro-benzene; acetonitrile;
2: |Diels-Alder Cycloaddition;
DOI:10.1002/anie.201402067
- Guidance literature:
-
Multi-step reaction with 3 steps
1: diethylamino-sulfur trifluoride / dichloromethane / 0.25 h / 0 °C / Inert atmosphere
2: dmap / acetonitrile / 1 h / 20 °C / Inert atmosphere
3: 1,3-bis-(1,3,5-trimethylphenyl)imidazol-2-ylidene / 1,2-dichloro-benzene / 6 h / 0 °C / Inert atmosphere; Reflux
With
dmap; diethylamino-sulfur trifluoride; 1,3-bis-(1,3,5-trimethylphenyl)imidazol-2-ylidene;
In
dichloromethane; 1,2-dichloro-benzene; acetonitrile;
3: |Diels-Alder Cycloaddition;
DOI:10.1002/anie.201402067
