3-{4-[(2-amino-4-phenyl-1,3-thiazol-5-yl)carbonyl]phenyl}propyl acetate

Base Information

Chemical Name:3-{4-[(2-amino-4-phenyl-1,3-thiazol-5-yl)carbonyl]phenyl}propyl acetate
CAS No.:1361414-39-2
Molecular Formula:C₂₁H₂₀N₂O₃S
Molecular Weight:380.467
Hs Code.:

Synonyms:3-{4-[(2-amino-4-phenyl-1,3-thiazol-5-yl)carbonyl]phenyl}propyl acetate

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Chemical Property of 3-{4-[(2-amino-4-phenyl-1,3-thiazol-5-yl)carbonyl]phenyl}propyl acetate

Chemical Property:

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Technology Process of 3-{4-[(2-amino-4-phenyl-1,3-thiazol-5-yl)carbonyl]phenyl}propyl acetate

There total 4 articles about 3-{4-[(2-amino-4-phenyl-1,3-thiazol-5-yl)carbonyl]phenyl}propyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1361414-38-1
3-[4-(2-bromoacetyl)phenyl]propyl acetate

: 1361413-53-7
N-(bis(4-methoxybenzyl)carbamothioyl)benzamide

: 1361414-39-2
3-{4-[(2-amino-4-phenyl-1,3-thiazol-5-yl)carbonyl]phenyl}propyl acetate

Guidance literature:: In N,N-dimethyl-formamide; at 85 ℃; for 0.75h; Inert atmosphere;

Reference yield:

: 122-97-4
3-Phenyl-1-propanol

: 1361414-39-2
3-{4-[(2-amino-4-phenyl-1,3-thiazol-5-yl)carbonyl]phenyl}propyl acetate

Guidance literature:: Multi-step reaction with 4 steps

1: dmap; triethylamine / dichloromethane / 1 h / 0 - 20 °C

2: aluminum (III) chloride / dichloromethane / 8 h / 0 °C / Inert atmosphere

3: bromine / diethyl ether / 1 h / 0 - 20 °C

4: N,N-dimethyl-formamide / 0.75 h / 85 °C / Inert atmosphere

With dmap; aluminum (III) chloride; bromine; triethylamine; In diethyl ether; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 58810-86-9
4’-(acetoxypropyl)acetophenone

: 1361414-39-2
3-{4-[(2-amino-4-phenyl-1,3-thiazol-5-yl)carbonyl]phenyl}propyl acetate

Guidance literature:: Multi-step reaction with 2 steps

1: bromine / diethyl ether / 1 h / 0 - 20 °C

2: N,N-dimethyl-formamide / 0.75 h / 85 °C / Inert atmosphere

With bromine; In diethyl ether; N,N-dimethyl-formamide;