1-Piperidinepropanoic acid, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, dihydrochloride, exo-

Base Information

Chemical Name:1-Piperidinepropanoic acid, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, dihydrochloride, exo-
CAS No.:87168-47-6
Molecular Formula:C₁₆H₂₈N₂O₂*2ClH
Molecular Weight:353.332
Hs Code.:
DSSTox Substance ID:DTXSID201007378

Synonyms:1-Piperidinepropanoic acid, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, dihydrochloride, exo-;exo-8-Methyl-8-azabicyclo(3.2.1)oct-3-yl-1-piperidinepropanoate dihydrochloride;1-Piperidinepropanoic acid, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, dihydrochloride, endo-;endo-8-Methyl-8-azabicyclo(3.2.1)oct-3-yl-1-piperidinepropanoate dihydrochloride;87168-46-5;87168-47-6;DTXSID201007378;LS-115983;LS-115984;8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 3-(piperidin-1-yl)propanoate--hydrogen chloride (1/2)

Suppliers and Price of 1-Piperidinepropanoic acid, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, dihydrochloride, exo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-Piperidinepropanoic acid, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, dihydrochloride, exo-

Chemical Property:

Vapor Pressure:4.51E-06mmHg at 25°C
Boiling Point:383.1°C at 760 mmHg
Flash Point:185.5°C
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:352.1684336
Heavy Atom Count:22
Complexity:327

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1C2CCC1CC(C2)OC(=O)CCN3CCCCC3.Cl.Cl

Technology Process of 1-Piperidinepropanoic acid, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, dihydrochloride, exo-

There total 4 articles about 1-Piperidinepropanoic acid, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, dihydrochloride, exo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.6%

: 110-89-4
piperidine

: Tropinyl-β-chloropropionate hydrochloride

: 87168-46-5,87168-47-6
3-Piperidin-1-yl-propionic acid (1R,3R,5S)-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester; hydrochloride

Guidance literature:: In ethanol; for 8h; Heating;
DOI:10.1007/BF00765640

Reference yield: 56.6%

: 110-89-4
piperidine

: 3-Chloro-propionic acid (1R,3S,5S)-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester; hydrochloride

: 87168-46-5,87168-47-6
3-Piperidin-1-yl-propionic acid (1R,3S,5S)-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester; hydrochloride

Guidance literature:: In ethanol; for 8h; Heating;
DOI:10.1007/BF00765640

Reference yield:

: 120-29-6
3-tropanol

: 87168-46-5,87168-47-6
3-Piperidin-1-yl-propionic acid (1R,3R,5S)-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / toluene / 4 h / Heating

2: 66.6 percent / ethanol / 8 h / Heating

In ethanol; toluene;
DOI:10.1007/BF00765640